1.14.11.56: L-proline cis-4-hydroxylase

This is an abbreviated version!
For detailed information about L-proline cis-4-hydroxylase, go to the full flat file.

Reaction

L-proline
+
2-oxoglutarate
+
O2
=
cis-4-hydroxy-L-proline
+
succinate
+
CO2

Synonyms

cis-P4H, MlP4H, mlr6283, R03107, SmP4H

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.56 L-proline cis-4-hydroxylase

Specific Activity

Specific Activity on EC 1.14.11.56 - L-proline cis-4-hydroxylase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.1
mutant V97F, product cis-3-hydroxy-L-pipecolic acid, pH 7.2, 30C
0.29
wild-type, product cis-5-hydroxy-L-pipecolic acid, pH 7.2, 30C
0.34
wild-type, product cis-3-hydroxy-L-pipecolic acid, pH 7.2, 30C
0.79
mutant V97F, product cis-5-hydroxy-L-pipecolic acid, pH 7.2, 30C
684
-
pH 7.5, 25C
707
-
pH 7.5, 25C