1.14.11.56: L-proline cis-4-hydroxylase

This is an abbreviated version!
For detailed information about L-proline cis-4-hydroxylase, go to the full flat file.

Reaction

L-proline
+
2-oxoglutarate
+
O2
=
cis-4-hydroxy-L-proline
+
succinate
+
CO2

Synonyms

cis-P4H, MlP4H, mlr6283, R03107, SmP4H

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.56 L-proline cis-4-hydroxylase

Reference

Reference on EC 1.14.11.56 - L-proline cis-4-hydroxylase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hara, R.; Kino, K.
Characterization of novel 2-oxoglutarate dependent dioxygenases converting L-proline to cis-4-hydroxy-L-proline
Biochem. Biophys. Res. Commun.
379
882-886
2009
Sinorhizobium meliloti (Q92LF6), Mesorhizobium loti (Q989T9), Mesorhizobium loti MAFF303099 (Q989T9)
Manually annotated by BRENDA team
Bach, T.M.; Hara, R.; Kino, K.; Ohtsu, I.; Yoshida, N.; Takagi, H.
Microbial production of N-acetyl cis-4-hydroxy-L-proline by coexpression of the Rhizobium L-proline cis-4-hydroxylase and the yeast N-acetyltransferase Mpr1
Appl. Microbiol. Biotechnol.
97
247-257
2013
Sinorhizobium meliloti
Manually annotated by BRENDA team
Koketsu, K.; Shomura, Y.; Moriwaki, K.; Hayashi, M.; Mitsuhashi, S.; Hara, R.; Kino, K.; Higuchi, Y.
Refined regio- and stereoselective hydroxylation of L-pipecolic acid by protein engineering of L-proline cis-4-hydroxylase based on the X-ray crystal structure
ACS Synth. Biol.
4
383-392
2015
Mesorhizobium loti (Q92LF6), Mesorhizobium loti (Q989T9), Mesorhizobium loti, Mesorhizobium loti MAFF303099 (Q989T9), Mesorhizobium loti 1021 (Q92LF6)
Manually annotated by BRENDA team
Koketsu, K.; Shomura, Y.; Moriwaki, K.; Hayashi, M.; Mitsuhashi, S.; Hara, R.; Kino, K.; Higuchi, Y.
Refined regio- and stereoselective hydroxylation of L-pipecolic acid by protein engineering of L-proline cis-4-hydroxylase based on the X-ray crystal structure
ACS Synth. Biol.
4
383-392
2015
Sinorhizobium meliloti (Q92LF6), Sinorhizobium meliloti, Mesorhizobium loti (Q989T9), Mesorhizobium loti
Manually annotated by BRENDA team