1.14.11.56: L-proline cis-4-hydroxylase

This is an abbreviated version!
For detailed information about L-proline cis-4-hydroxylase, go to the full flat file.

Reaction

L-proline
+
2-oxoglutarate
+
O2
=
cis-4-hydroxy-L-proline
+
succinate
+
CO2

Synonyms

cis-P4H, MlP4H, mlr6283, R03107, SmP4H

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.56 L-proline cis-4-hydroxylase

Natural Substrates Products

Natural Substrates Products on EC 1.14.11.56 - L-proline cis-4-hydroxylase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
L-pipecolate + 2-oxoglutarate + O2
cis-5-hydroxypipecolate + cis-3-hydroxypipecolate + succinate + CO2
show the reaction diagram
L-proline + 2-oxoglutarate + O2
cis-4-hydroxy-L-proline + succinate + CO2
show the reaction diagram