1.14.11.55: ectoine hydroxylase
This is an abbreviated version!
For detailed information about ectoine hydroxylase, go to the full flat file.
Word Map on EC 1.14.11.55
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1.14.11.55
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2-oxoglutarate-dependent
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halophil
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5-hydroxyectoine
-
halomonas
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salexigens
-
ironii
-
non-heme-containing
-
hydroxylases
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alaskensis
-
sphingopyxis
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elongata
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stereo-specific
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osmostress
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mechanosensitive
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tetrahydropyrimidine
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ectabc
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stutzeri
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osmolarity
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virgibacillus
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co-substrate
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halotolerant
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maritimus
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chassis
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salina
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region-selective
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thermoregulated
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nitrosopumilus
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chromohalobacter
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thermoprotection
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alkaliphilic
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hydrothermalis
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sitting-drop
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synthesis
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extremophiles
-
prop
-
apo-form
-
monosodium
- 1.14.11.55
-
2-oxoglutarate-dependent
-
halophil
- 5-hydroxyectoine
-
halomonas
- salexigens
-
ironii
-
non-heme-containing
- hydroxylases
- alaskensis
-
sphingopyxis
- elongata
-
stereo-specific
-
osmostress
-
mechanosensitive
-
tetrahydropyrimidine
-
ectabc
- stutzeri
-
osmolarity
-
virgibacillus
-
co-substrate
-
halotolerant
- maritimus
-
chassis
- salina
-
region-selective
-
thermoregulated
- nitrosopumilus
-
chromohalobacter
-
thermoprotection
-
alkaliphilic
- hydrothermalis
-
sitting-drop
- synthesis
-
extremophiles
-
prop
-
apo-form
-
monosodium
Reaction
Synonyms
Csal_3003, ectD, EctE, ectoine dioxygenase, HELO_4008, REctD, Sala_2952, SCATT_10620, ThpD
ECTree
1.14.11.55 ectoine hydroxylaseAdvanced search results
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results (Engineering
Engineering on EC 1.14.11.55 - ectoine hydroxylase
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PROTEIN VARIANTS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
E140A
residue involved in dimerization, activity similar to wild-type
Q127A
residue involved in ectoine binding, about 1% of wild-type activity
R139A
residue involved in dimerization, activity similar to wild-type
R139A/E140A
residues involved in dimerization, activity similar to wild-type
R280A
residue involved in ectoine binding, about 8% of wild-type activity
T149A
residue involved in ectoine binding, about 4% of wild-type activity
W150A
residue involved in ectoine binding, about 2% of wild-type activity
E140A
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residue involved in dimerization, activity similar to wild-type
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Q127A
-
residue involved in ectoine binding, about 1% of wild-type activity
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R139A
-
residue involved in dimerization, activity similar to wild-type
-
R280A
-
residue involved in ectoine binding, about 8% of wild-type activity
-
T149A
-
residue involved in ectoine binding, about 4% of wild-type activity
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A163C
A163C/S244C
D148A
D148E
F143A
F143W
F143Y
F242A
F242W
F242Y
F263A
F263W
F263Y
F95A
H146A
H248A
N133A
N261A
P198A
Q129A
R131A
R259A
R259H
R259K
R259Q
S165A
S167A
S205A
S244C
S250A
V265A
V265L
V265T
W152A
W152F
W152Y
A163C
the mutant shows reduced activity compared to the wild type enzyme
A163C/S244C
the mutant shows increased activity compared to the wild type enzyme
D148A
loss of activity. Residue is involved in binding of Fe2+
D148E
loss of activity. Residue is involved in binding of Fe2+
F143A
loss of activity. Residue is involved in binding of 2-oxoglutarate
F143W
loss of activity. Residue is involved in binding of 2-oxoglutarate
F143Y
loss of activity. Residue is involved in binding of 2-oxoglutarate
F242A
loss of activity. Residue is involved in binding of ectoine
F242W
loss of activity. Residue is involved in binding of ectoine
F242Y
the mutant shows reduced activity compared to the wild type enzyme
F263A
loss of activity. Residue is involved in binding of ectoine
F263W
loss of activity. Residue is involved in binding of ectoine
F263Y
the mutant shows reduced activity compared to the wild type enzyme
F95A
loss of activity. Residue is involved in binding of 2-oxoglutarate
H146A
loss of activity. Residue is involved in binding of Fe2+
H248A
loss of activity. Residue is involved in binding of Fe2+
N133A
loss of activity. Residue is involved in binding of 2-oxoglutarate
N261A
the mutant shows reduced activity compared to the wild type enzyme
P198A
the mutant shows reduced activity compared to the wild type enzyme
Q129A
loss of activity. Residue is involved in binding of ectoine
R131A
loss of activity. Residue is involved in binding of 2-oxoglutarate
R259A
loss of activity. Residue is involved in binding of 2-oxoglutarate
R259H
loss of activity. Residue is involved in binding of 2-oxoglutarate
R259K
loss of activity. Residue is involved in binding of 2-oxoglutarate
R259Q
loss of activity. Residue is involved in binding of 2-oxoglutarate
S165A
the mutant shows reduced activity compared to the wild type enzyme
S205A
the mutant shows reduced activity compared to the wild type enzyme
S244C
the mutant shows reduced activity compared to the wild type enzyme
S250A
loss of activity. Residue is involved in binding of 2-oxoglutarate
V265A
the mutant shows reduced activity compared to the wild type enzyme
V265L
the mutant shows reduced activity compared to the wild type enzyme
V265T
the mutant shows reduced activity compared to the wild type enzyme
W152A
loss of activity. Residue is involved in binding of ectoine
W152F
loss of activity. Residue is involved in binding of ectoine
W152Y
loss of activity. Residue is involved in binding of ectoine
