1.14.11.53: mRNA N6-methyladenine demethylase

This is an abbreviated version!
For detailed information about mRNA N6-methyladenine demethylase, go to the full flat file.

Reaction

Synonyms

AlkB homolog 5, ALKBH10B, ALKBH5, ALKBH5 demethylase, ALKBH9B, alkylation repair homolog protein 5, fat mass and obesity-associated enzyme, fat mass and obesity-associated protein, FTO, m6A mRNA demethylase, m6A RNA demethylase, m6A-RNA demethylase, N6-methyladenosine demethylase, RNA N6-methyladenine demethylase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

                1.14.11.53 mRNA N6-methyladenine demethylase

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Results

in table

1918

AA Sequence

7

Application

10

Cloned(Commentary)

6

Crystallization (Commentary)

777

Disease/ Diagnostics

4

Expression

26

General Information

2

General Stability

11

IC50 Value

23

Inhibitors

10

kcat/KM [mM/s]

11

KM Value [mM]

8

Localization

8

Metals/Ions

2

Molecular Weight [Da]

21

Natural Substrates/ Products (Substrates)

45

Organism

14

PDB ID

6

pH Optimum

1

Posttranslational Modification

21

Protein Variants

12

Purification (Commentary)

1

Reaction

44

Reference

42

Source Tissue

53

Substrates and Products (Substrate)

3

Subunits

53

Synonyms

1

Systematic Name

5

Temperature Optimum [°C]

10

Turnover Number [1/s]