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1.14.11.48: xanthine dioxygenase

This is an abbreviated version!
For detailed information about xanthine dioxygenase, go to the full flat file.

Reaction

xanthine
+
2-oxoglutarate
+
O2
=
Urate
+
succinate
+
CO2

Synonyms

alpha-ketoglutarate-dependent xanthine hydroxylase, AO090001000152, TauD domain-containing protein, XanA, xanthine/alpha-ketoglutarate dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.48 xanthine dioxygenase

Reference

Reference on EC 1.14.11.48 - xanthine dioxygenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Li, M.; Muller, T.A.; Fraser, B.A.; Hausinger, R.P.
Characterization of active site variants of xanthine hydroxylase from Aspergillus nidulans
Arch. Biochem. Biophys.
470
44-53
2008
Aspergillus nidulans (Q4QZZ9)
Manually annotated by BRENDA team
Montero-Moran, G.M.; Li, M.; Rendon-Huerta, E.; Jourdan, F.; Lowe, D.J.; Stumpff-Kane, A.W.; Feig, M.; Scazzocchio, C.; Hausinger, R.P.
Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans
Biochemistry
46
5293-5304
2007
Aspergillus nidulans
Manually annotated by BRENDA team
Cultrone, A.; Scazzocchio, C.; Rochet, M.; Montero-Moran, G.; Drevet, C.; Fernandez-Martin, R.
Convergent evolution of hydroxylation mechanisms in the fungal kingdom: molybdenum cofactor-independent hydroxylation of xanthine via alpha-ketoglutarate-dependent dioxygenases
Mol. Microbiol.
57
276-290
2005
Aspergillus nidulans (Q4QZZ9)
Manually annotated by BRENDA team
Bocanegra-Jimenez, F.Y.; Montero-Moran, G.M.; Lara-Gonzalez, S.
Purification and characterization of an FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus oryzae
Protein Expr. Purif.
183
105862
2021
Aspergillus oryzae (Q2UP14), Aspergillus oryzae, Aspergillus oryzae ATCC 42149 (Q2UP14)
Manually annotated by BRENDA team