1.14.11.45: L-isoleucine 4-hydroxylase
This is an abbreviated version!
For detailed information about L-isoleucine 4-hydroxylase, go to the full flat file.
Word Map on EC 1.14.11.45
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1.14.11.45
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4-hydroxyisoleucine
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corynebacterium
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glutamicum
-
thuringiensis
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l-ile
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lactofermentum
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insulinotropic
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stereoselectively
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bl21de3
- 1.14.11.45
-
4-hydroxyisoleucine
-
corynebacterium
- glutamicum
- thuringiensis
- l-ile
- lactofermentum
-
insulinotropic
-
stereoselectively
-
bl21de3
Reaction
Synonyms
IDO, isoleucine 4-hydroxylase, L-isoleucine dioxygenase
ECTree
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Reference on EC 1.14.11.45 - L-isoleucine 4-hydroxylase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hibi, M.; Kawashima, T.; Kodera, T.; Smirnov, S.; Sokolov, P.; Sugiyama, M.; Shimizu, S.; Yokozeki, K.; Ogawa, J.
Characterization of Bacillus thuringiensis L-isoleucine dioxygenase for production of useful amino acids
Appl. Environ. Microbiol.
77
6926-6930
2011
Bacillus thuringiensis, Bacillus thuringiensis 2e2
Kodera, T.; Smirnov, S.; Samsonova, N.; Kozlov, Y.; Koyama, R.; Hibi, M.; Ogawa, J.; Yokozeki, K.; Shimizu, S.
A novel l-isoleucine hydroxylating enzyme, l-isoleucine dioxygenase from Bacillus thuringiensis, produces (2S,3R,4S)-4-hydroxyisoleucine
Biochem. Biophys. Res. Commun.
390
506-510
2009
Bacillus thuringiensis, Bacillus thuringiensis 2e2 AKU 0251
Smirnov, S.V.; Sokolov, P.M.; Kodera, T.; Sugiyama, M.; Hibi, M.; Shimizu, S.; Yokozeki, K.; Ogawa, J.
A novel family of bacterial dioxygenases that catalyse the hydroxylation of free L-amino acids
FEMS Microbiol. Lett.
331
97-104
2012
Bacillus thuringiensis (E2GIN1), Bacillus thuringiensis 2-e-2 (E2GIN1)
Hibi, M.; Kawashima, T.; Yajima, H.; Smirnov, S.; Kodera, T.; Sugiyama, M.; Shimizu, S.; Yokozeki, K.; Ogawa, J.
Enzymatic synthesis of chiral amino acid sulfoxides by Fe(II)/alpha-ketoglutarate-dependent dioxygenase
Tetrahedron Asymmetry
24
990-994
2013
Bacillus thuringiensis, Bacillus thuringiensis 2e2
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Shi, F.; Niu, T.; Fang, H.
4-Hydroxyisoleucine production of recombinant Corynebacterium glutamicum ssp. lactofermentum under optimal corn steep liquor limitation
Appl. Microbiol. Biotechnol.
99
3851-3863
2015
Bacillus thuringiensis, Bacillus thuringiensis YBT-1520
Shi, F.; Fang, H.; Niu, T.; Lu, Z.
Overexpression of ppc and lysC to improve the production of 4-hydroxyisoleucine and its precursor L-isoleucine in recombinant Corynebacterium glutamicum ssp. lactofermentum
Enzyme Microb. Technol.
87-88
79-85
2016
Bacillus thuringiensis, Bacillus thuringiensis YBT-1520
Zhang, C.; Liu, Y.; Xue, N.; Wang, X.; Xie, X.; Xu, Q.; Chen, N.
Characterization of recombinant L-isoleucine-4-hydroxylase from Bacillus thuringiensis and its application in 4-hydroxyisoleucine biosynthesis
Wei Sheng Wu Xue Bao
54
889-896
2014
Bacillus thuringiensis (S5SPJ1), Bacillus thuringiensis TCCC 11826 (S5SPJ1)
An, J.; Zhang, W.; Jing, X.; Nie, Y.; Xu, Y.
Reconstitution of TCA cycle involving L-isoleucine dioxygenase for hydroxylation of L-isoleucine in Escherichia coli using CRISPR-Cas9
3 Biotech
10
167
2020
Bacillus sp. (in: Bacteria)
Tan, S.; Shi, F.; Liu, H.; Yu, X.; Wei, S.; Fan, Z.; Li, Y.
Dynamic control of 4-hydroxyisoleucine biosynthesis by modified L-isoleucine biosensor in recombinant Corynebacterium glutamicum
ACS Synth. Biol.
9
2378-2389
2020
Corynebacterium glutamicum
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Yu, X.; Shi, F.; Liu, H.; Tan, S.; Li, Y.
Programming adaptive laboratory evolution of 4-hydroxyisoleucine production driven by a lysine biosensor in Corynebacterium glutamicum
AMB Express
11
66
2021
Bacillus thuringiensis (E2GIN1)
Zhang, C.; Ma, J.; Li, Z.; Liang, Y.; Xu, Q.; Xie, X.; Chen, N.
A strategy for L-isoleucine dioxygenase screening and 4-hydroxyisoleucine production by resting cells
Bioengineered
9
72-79
2018
Bacillus thuringiensis (S5SPJ1)
Huang, S.; Shi, F.
Directed evolution and site-specific mutagenesis of L-isoleucine dioxygenase derived from Bacillus weihenstephanensis
Biotechnol. Lett.
40
1227-1235
2018
Bacillus mycoides
Shi, F.; Fan, Z.; Zhang, S.; Wang, Y.; Tan, S.; Li, Y.
Optimization of ribosomal binding site sequences for gene expression and 4-hydroxyisoleucine biosynthesis in recombinant corynebacterium glutamicum
Enzyme Microb. Technol.
140
109622
2020
Bacillus thuringiensis (E2GIN1)
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