1.14.11.17: taurine dioxygenase

This is an abbreviated version!
For detailed information about taurine dioxygenase, go to the full flat file.

Reaction

Synonyms

2-aminoethanesulfonate dioxygenase, 2-aminoethanesulfonic acid/alpha-ketoglutarate dioxygenase, alpha-ketoglutarate-dependent dioxygenase, alpha-ketoglutarate-dependent taurine dioxygenase, alpha-ketoglutarate/taurine dioxygenase, AtsK, Fe(II)/2-oxoglutarate-dependent taurine dioxygenase, Fe(II)/alpha-ketoglutarate-dependent taurine dioxygenase, oxygenative alkylsulfatase, SSI3, TauD, TauD-{FeNO}7, taurine (2-aminoethanesulfonate)/2-oxoglutarate dioxygenase, taurine alpha ketoglutarate dioxygenase, taurine alpha-ketoglutarate dioxygenase, taurine dioxygenase, taurine hydroxylase, taurine-alpha-ketoglutarate dioxygenase, taurine/2-oxoglutarate dioxygenase, taurine/alpha-ketoglutarate dioxygenase, taurine/alpha-ketoglutarate-dependent dioxygenase, taurine/alphaKG dioxygenase, taurine/alphaKGD, taurine: alpha-ketoglutarate dioxygenase, taurine:2OG dioxygenase, taurine:alpha-ketoglutarate dioxygenase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

                1.14.11.17 taurine dioxygenase

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Results	in table
3	Activating Compound
2975	AA Sequence
2	Application
3	CAS Registry Number
10	Cloned(Commentary)
8	Crystallization (Commentary)
8	Disease/ Diagnostics
14	General Information
4	IC50 Value
12	Inhibitors
6	kcat/KM [mM/s]
1	Ki Value [mM]
30	KM Value [mM]
29	Metals/Ions
13	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
64	Organism
5	Pathway
38	PDB ID
6	pH Optimum
1	Posttranslational Modification
33	Protein Variants
12	Purification (Commentary)
5	Reaction
12	Reaction Type
43	Reference
4	Specific Activity [micromol/min/mg]
2	Storage Stability
58	Substrates and Products (Substrate)
13	Subunits
69	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Stability [°C]
11	Turnover Number [1/s]

Disease

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Disease on EC 1.14.11.17 - taurine dioxygenase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Infections

m6A mRNA Methylation Regulates Epithelial Innate Antimicrobial Defense Against Cryptosporidial Infection.

34295340

Neoplasms

ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-?B pathway.

33302959

Urinary Bladder Neoplasms

The tumor-suppressive effects of alpha-ketoglutarate-dependent dioxygenase FTO via N6-methyladenosine RNA methylation on bladder cancer patients.

34499008

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