1.14.11.13: gibberellin 2beta-dioxygenase

This is an abbreviated version!
For detailed information about gibberellin 2beta-dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.13

Reaction

gibberellin 1
+
2-oxoglutarate
+
O2
=
2beta-hydroxygibberellin 1
+
succinate
+
CO2

Synonyms

2-oxoglutarate-dependent dioxygenase of gibberellin biosynthesis, AaGA2ox1, AaGA2ox2, AaGA2ox3, AaGA2ox4, AtGA2ox2, AtGA2ox8, C19-GA 2-oxidase, C20 GA2ox, C20-gibberellin deactivation enzyme, GA 2-ox, GA 2-oxidase, GA 2-oxidase 6, GA 2-oxidase 7, GA 2-oxidase A1, GA 2-oxidase1, GA 2-oxidase3, GA 2beta,3beta-hydroxylase, GA 2ODD, GA2ox, GA2ox1, GA2ox2, GA2ox3, GA2ox4, GA2ox5, GA2ox6, GA2ox7, gibberellin 2-oxidase, gibberellin 2-oxidase 1, gibberellin 2-oxidase 2, gibberellin 2-oxidase 3, gibberellin 2-oxidase 4, gibberellin 2-oxidase 6, gibberellin 2beta-hydroxylase, giberellin 2-oxidase 2, MdGA2ox1, PsGA2ox1, PsGA2ox2, PvGA2ox5b, PvGA2ox9a

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.13 gibberellin 2beta-dioxygenase

Inhibitors

Inhibitors on EC 1.14.11.13 - gibberellin 2beta-dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-chloroindole-3-acetic acid
auxin hormone from seeds decreases PsGA2ox1 mRNA levels 2 h after application to deseeded pericarps and remains low throughout the treatment period
gibberellin 1
gibberellin 3
gibberellin 4
-
50% inhibition at 0.2-0.3 nmol
gibberellin 4 methyl ester
-
inhibits oxidation of 16,17-dihydro gibberellin 4
gibberellin 5
-
strong inhibition of the conversion of gibberellin 20
gibberellin 9
-
50% inhibition at 11 nmol
Gibberellin methyl ester
-
-
indole-3-acetic acid
auxin hormone from seeds decreases PsGA2ox1 mRNA levels 2 h after application to deseeded pericarps, sharply increases after 4 h and stays elevated
methyl 6-chloro-3H-1,2,3-benzodithiazole-4-carboxylate 2-oxide
-
highly specific inhibitor of gibberellin 2-oxidase, evaluation as inhibitor of gibberellin catabolism in planta. The compound promotes both the germination and elongation of Arabidopsis seedlings
N,N-dimethyl succinic acid hydrazide
-
-
prohexadione
-
inhibits gibberellin 2-oxidase, but is not effective in promoting germination and elongation of Arabidopsis seedlings
succinic acid
-
-
additional information
-
inhibitor development block GA catabolism in plants, in vitro random screening, overview. No or poor inhibition by 2-acetamido-5-chlorobenzoic acid methylester, 5-chlorooxindole, 6-chloro-2-mercaptobenzothiazole, 7-chloro-2H-1,4-benzothiazin-3(4H)-one, methyl 5-chloroanthranilate, methyl 5-chloro-2-nitrobenzoate, methyl 3-chlorobenzoate
-