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1.14.11.13: gibberellin 2beta-dioxygenase

This is an abbreviated version!
For detailed information about gibberellin 2beta-dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.13

Reaction

gibberellin 1
+
2-oxoglutarate
+
O2
=
2beta-hydroxygibberellin 1
+
succinate
+
CO2

Synonyms

2-oxoglutarate-dependent dioxygenase, AaGA2ox1, AaGA2ox2, AaGA2ox3, AaGA2ox4, AtGA2ox10, AtGA2ox2, AtGA2ox8, AtGA2ox9, BnGA2ox2, C19-GA 2-oxidase, C20 GA2ox, C20-gibberellin deactivation enzyme, CuGA2ox2/3, CuGA2ox4, CuGA2ox8, GA 2-ox, GA 2-oxidase, GA 2-oxidase 6, GA 2-oxidase 7, GA 2-oxidase A1, GA 2-oxidase1, GA 2-oxidase3, GA 2beta,3beta-hydroxylase, GA 2ODD, GA2-oxidaseA9, GA2ox, GA2ox1, GA2ox2, GA2ox3, GA2ox4, GA2ox5, GA2ox6, GA2ox7, GA2oxA13, GA2oxA9, GA2oxidase 7, gibberellin 2-oxidase, gibberellin 2-oxidase 1, gibberellin 2-oxidase 2, gibberellin 2-oxidase 3, gibberellin 2-oxidase 4, gibberellin 2-oxidase 6, gibberellin 2beta-hydroxylase, gibberellin GA2oxidaseA13, giberellin 2-oxidase 2, JcGA2ox6, MdGA2ox1, PpGA2ox, PsGA2ox1, PsGA2ox2, PvGA2ox5b, PvGA2ox9a, SBI(SV14), SBI(Zhu1S), Solyc02g080120

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.13 gibberellin 2beta-dioxygenase

Expression

Expression on EC 1.14.11.13 - gibberellin 2beta-dioxygenase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
expression of PpGA2ox can be up-regulated by 10 microM gibberellic acid, 0.005 mM methyl jasmonate, or 0.1 mM indole-3-acetic acid. In addition, its native promoter can drive GUS expression in both leaf apex and shoot apical region
GA biosynthesis inhibitor, paclobutrazol, positively regulates the OsGA2ox6 gene
-
helix-loop-helix transcription factor CESTA(CES)/BRASSINOSTEROID-ENHANCED EXPRESSION(BEE) can induce the expression of the class III gibberellin 2-oxidase GA2ox7. CES directly binds to the GA2ox7 promoter and is activated by brassinosteroids
overexpression of two gibberellin 2beta-dioxygenase genes, that is PvGA2ox5 and PvGA2ox9, results in characteristic gibberellin-deficient phenotypes with dark-green leaves and modified plant architecture. The changes in plant morphology appear to be associated with GA2ox transcript abundance. Exogenous application of GA rescues the GA-deficient phenotypes in transgenic lines. Transgenic semi-dwarf lines display increased tillering and reduced lignin content, and the syringyl/guaiacyl lignin monomer ratio accompanied by the reduced expression of lignin biosynthetic genes compared to nontransgenic plants. A moderate increase in the level of glucose release in these transgenic lines might be attributed to reduced biomass recalcitrance as a result of reduced lignin content and lignin composition. Overexpression of GA2ox genes in switchgrass is a feasible strategy to improve plant architecture and reduce biomass recalcitrance for biofuel
-
Rht18 semidwarfism is associated with increased expression of GA2oxA9
-
treatments of drought or high salinity increase the expression