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1.13.11.75: all-trans-8'-apo-beta-carotenal 15,15'-oxygenase

This is an abbreviated version!
For detailed information about all-trans-8'-apo-beta-carotenal 15,15'-oxygenase, go to the full flat file.

Word Map on EC 1.13.11.75

Reaction

all-trans-8'-apo-beta-carotenal
+
O2
=
all-trans-retinal
 +
(2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial

Synonyms

ACO, apo-carotenoid oxygenase, apocarotenoid cleavage oxygenase, apocarotenoid oxygenase, apocarotenoid-15,15'-oxygenase, apocarotenoid-15-15'-oxygenase, carotenoid cleavage oxygenase, CCO, Diox1, EC 1.14.99.41, More, sll1541

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.75 all-trans-8'-apo-beta-carotenal 15,15'-oxygenase

Inhibitors

Inhibitors on EC 1.13.11.75 - all-trans-8'-apo-beta-carotenal 15,15'-oxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
CHAPS
slight inhibition
CYMAL-4
slight inhibition
hexaethylene glycol monooctyl ether
strongly inhibits ACO activity even at concentrations below its critical micelle concentration
tetraethylene glycol monooctyl ether
strongly inhibits ACO activity even at concentrations below its critical micelle concentration
additional information
the enzyme ACO is inhibited by linear polyoxyethylene detergents, mechanism, overview. ACO crystallization strongly inhibits the apocarotenoid oxygenase activity of the enzyme. PEG 3350 has little influence on enzyme activity up to a concentration of10% w/v
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