1.13.11.66: hydroquinone 1,2-dioxygenase

This is an abbreviated version!
For detailed information about hydroquinone 1,2-dioxygenase, go to the full flat file.

Reaction

Synonyms

HQDO, hydroquinone 1,2-dioxygenase, hydroquinone dioxygenase, LinE, mnpC, PcpA, PdcDE, PnpC1, PnpC2, PnpCD, ring-cleavage hydroquinone 1,2-dioxygenase, two-subunit hydroquinone 1,2-dioxygenase, type II HQDO, YaiA

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.66 hydroquinone 1,2-dioxygenase

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Results	in table
1	Activating Compound
35	AA Sequence
7	Cloned(Commentary)
3	Crystallization (Commentary)
2	Expression
7	General Information
1	General Stability
27	Inhibitors
10	kcat/KM [mM/s]
1	Ki Value [mM]
17	KM Value [mM]
15	Metals/Ions
12	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
66	Organism
5	Pathway
7	pH Optimum
4	pH Range
2	pH Stability
19	Protein Variants
6	Purification (Commentary)
3	Reaction
25	Reference
5	Specific Activity [micromol/min/mg]
3	Storage Stability
75	Substrates and Products (Substrate)
20	Subunits
27	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
12	Turnover Number [1/s]

KM Value

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KM Value on EC 1.13.11.66 - hydroquinone 1,2-dioxygenase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0013

2,6-dibromohydroquinone

Sphingobium chlorophenolicum

Q9ZBB0

pH 7.0, 23°C

718916

0.0135

2,6-dichloro-p-hydroquinone

Sphingobium chlorophenolicum

Q9ZBB0

pH 6.7, 22°C

718727

0.0032

2,6-dichlorohydroquinone

Sphingobium chlorophenolicum

Q9ZBB0

pH 7.0, 23°C

718916

0.055

2,6-dimethylhydroquinone

Sphingobium chlorophenolicum

Q9ZBB0

pH 7.0, 23°C

718916

0.0044

2-chloro-6-methylhydroquinone

Sphingobium chlorophenolicum

Q9ZBB0

pH 7.0, 23°C

718916

0.2

2-methylhydroquinone

Lactococcus lactis

-

pH 6.4, 30°C, recombinant enzyme

745802

0.0085

bromohydroquinone

Sphingobium chlorophenolicum

Q9ZBB0

pH 7.0, 23°C

718916

0.01

chlorohydroquinone

Sphingobium chlorophenolicum

Q9ZBB0

pH 7.0, 23°C

718916

0.0022 - 0.255

hydroquinone

3 entries

0.041

methylhydroquinone

Sphingobium chlorophenolicum

Q9ZBB0

pH 7.0, 23°C

718916

0.021 - 0.26

O2

5 entries

0.0022

hydroquinone

Sphingomonas sp.

F8TW82, F8TW83

pH 7.0, 25°C

718555

0.037

hydroquinone

Pseudomonas fluorescens

-

pH 7.0, 25°C

719714

0.255

hydroquinone

Cupriavidus necator

-

pH 7.4, temperature not specified in the publication

719327

0.021

O2

Sphingobium chlorophenolicum

Q9ZBB0

cosubstrate 2-chloro-6-methylhydroquinone, 1,2-cleavage, pH 7.0, 23°C

718916

0.07

O2

Sphingobium chlorophenolicum

Q9ZBB0

cosubstrate 2,6-dimethylhydroquinone, pH 7.0, 23°C

718916

0.12

O2

Sphingobium chlorophenolicum

Q9ZBB0

cosubstrate 2,6-dibromohydroquinone, pH 7.0, 23°C

718916

0.19

O2

Sphingobium chlorophenolicum

Q9ZBB0

cosubstrate 2,6-dichlorohydroquinone, pH 7.0, 23°C

718916

0.26

O2

Sphingobium chlorophenolicum

Q9ZBB0

cosubstrate 2-chloro-6-methylhydroquinone, 1,6-cleavage, pH 7.0, 23°C

718916