1.13.11.66: hydroquinone 1,2-dioxygenase

This is an abbreviated version!
For detailed information about hydroquinone 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.66

Reaction

benzene-1,4-diol
+
O2
=
(2Z,4E)-4-hydroxy-6-oxohexa-2,4-dienoate

Synonyms

HQDO, hydroquinone 1,2-dioxygenase, hydroquinone dioxygenase, LinE, mnpC, PcpA, PdcDE, PnpC1, PnpC2, PnpCD, two-subunit hydroquinone 1,2-dioxygenase, type II HQDO, YaiA

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.66 hydroquinone 1,2-dioxygenase

Inhibitors

Inhibitors on EC 1.13.11.66 - hydroquinone 1,2-dioxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-dipyridyl
-
inactivation
2,6-dibromophenol
-
competitive
3,4-dihydroxybenzoate
0.2 mM, 94% inhibition; 0.2 mM, 94% inhibition
3-bromocatechol
-
inactivation
4-coumaric acid
0.2 mM, 97% inhibition; 0.2 mM, 97% inhibition
4-hydroxybenzoate
4-Hydroxybenzonitrile
-
0.2 mM, no residual activity
4-hydroxycinnamate
-
0.2 mM, no residual activity
4-nitrophenol
bromohydroquinone
-
substrate inhibition
caffeic acid
0.2 mM, 98% inhibition; 0.2 mM, 98% inhibition
catechol
0.2 mM, 93% inhibition; 0.2 mM, 93% inhibition
chlorohydroquinone
-
substrate inhibition
hydrogen peroxide
-
inactivation
Hydroxyhydroquinone
-
0.2 mM, 9% residual activity
methoxyhydroquinone
-
strong substrtae inhibition
o-phenanthroline
-
inactivation
ortho-disubstituted phenols
-
-
-
phenol
0.2 mM, 98% inhibition; 0.2 mM, 98% inhibition
resorcinol
0.2 mM, 99% inhibition; 0.2 mM, 99% inhibition
vanillate
0.2 mM, 86% inhibition; 0.2 mM, 86% inhibition
Vanillyl alcohol
0.2 mM, 62% inhibition; 0.2 mM, 62% inhibition
additional information
-