1.13.11.58: linoleate 9S-lipoxygenase

This is an abbreviated version!
For detailed information about linoleate 9S-lipoxygenase, go to the full flat file.

Reaction

Synonyms

15-LOX, 9-lipoxygenase, 9-LO, 9-LOX, 9LOX, 9S-lipoxygenase, arachidonate 9S-LOX, AtLOX-1, AtLOX-5, AtLOX1, AtLOX5, CaLOX1, eLOX3, epidermal lipoxygenase-3, GhLOX1, L-2, linoleate 9-lipoxygenase, linoleate 9S-lipoxygenase, linoleate 9S-lipoxygenase 1, linoleate 9S-lipoxygenase 2, linoleate 9S-lipoxygenase 3, linoleate oxygen oxidoreductase, lipoxygenase, LOX, LOX1, LOX1.1, LOX1.3, LOX12, LOX13, LOX14, LOX1:Md:1c, LOX1c, LOX2, LOX3, LOX4, LOX5, LOX6, LOX7, LOX8, LOX9, LoxA, Nb-9-LOX, Osr9-LOX1, plant LOX-1, POTLX-1, r9-LOX1, seed linoleate 9S-lipoxygenase-3, StLOX1, tuberization protein, type-1 9-LOX, ZmLOX3, ZmLOX5

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.58 linoleate 9S-lipoxygenase

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Results	in table
1	Activating Compound
63	AA Sequence
2	Application
22	Cloned(Commentary)
1	Crystallization (Commentary)
17	Disease/ Diagnostics
19	Expression
28	General Information
14	IC50 Value
15	Inhibitors
5	kcat/KM [mM/s]
11	KM Value [mM]
9	Localization
2	Metals/Ions
8	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
49	Organism
7	Pathway
13	PDB ID
12	pH Optimum
5	pH Range
5	pI Value
10	Protein Variants
11	Purification (Commentary)
1	Reaction
47	Reference
47	Source Tissue
1	Specific Activity [micromol/min/mg]
72	Substrates and Products (Substrate)
10	Subunits
118	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
3	Temperature Range [°C]
8	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 1.13.11.58 - linoleate 9S-lipoxygenase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.00456

1-[5-(2-phenyl-1H-indol-3-yl)-3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one

Glycine max

P09186

pH not specified in the publication, temperature not specified in the publication

764620

-

0.00384

2-phenyl-3-[3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-5-yl]-1H-indole

Glycine max

P09186

pH not specified in the publication, temperature not specified in the publication

764620

-

0.00489

2-phenyl-3-[3-(pyridin-4-yl)-4,5-dihydro-1,2-oxazol-5-yl]-1H-indole

Glycine max

P09186

pH not specified in the publication, temperature not specified in the publication

764620

-

0.018

4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine

Glycine max

P09186

pH 7, 30°C

764556

-

0.0008

5-farnesyloxycoumarin

Glycine max

P09186

pH 7, 30°C

764556

-

0.0021

6-farnesyloxycoumarin

Glycine max

P09186

pH 7, 30°C

764556

-

0.00068

7-farnesyloxy-3-acetylcoumarin

Glycine max

P09186

pH 7, 30°C

764556

-

0.0031

7-farnesyloxycoumarin

Glycine max

P09186

pH 7, 30°C

764556

-

0.0033

7-geranyloxy-3-acetylcoumarin

Glycine max

P09186

pH 7, 30°C

764556

-

0.00146

8-farnesyloxy-3-acetylcoumarin

Glycine max

P09186

pH 7, 30°C

764556

-

0.0058

8-farnesyloxycoumarin

Glycine max

P09186

pH 7, 30°C

764556

-

0.0041

8-geranyloxy-3-acetylcoumarin

Glycine max

P09186

pH 7, 30°C

764556

-

0.00012

ethyl 2-[(2E)-2-benzylidenehydrazinyl]-4-methyl-1,3-thiazole-5-carboxylate

Glycine max

P09186

pH 8.0, 25°C

764064

-

0.00021

ethyl 4-methyl-2-[(2E)-2-[(3-nitrophenyl)methylidene]hydrazinyl]-1,3-thiazole-5-carboxylate

Glycine max

P09186

pH 8.0, 25°C

764064

-