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1.13.11.23: 2,3-dihydroxyindole 2,3-dioxygenase

This is an abbreviated version!
For detailed information about 2,3-dihydroxyindole 2,3-dioxygenase, go to the full flat file.

Reaction

2,3-Dihydroxyindole
+
O2
=
anthranilate
+
CO2

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.23 2,3-dihydroxyindole 2,3-dioxygenase

Inhibitors

Inhibitors on EC 1.13.11.23 - 2,3-dihydroxyindole 2,3-dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,3-Dimercaptopropanol
-
47% inhibition at 1 mM, 59% inhibition at 5 mM
ascorbic acid
-
30% inhibition at 1 mM
catechol
-
45% inhibition at 1 mM
o-phenanthroline
-
46% inhibition at 1 mM