1.13.11.20: cysteine dioxygenase

This is an abbreviated version!
For detailed information about cysteine dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.20

Reaction

L-cysteine
+
O2
=
3-sulfinoalanine

Synonyms

3-mercaptopropionate dioxygenase, Arg-type CDO, BsCDO, CDO, CDO1, CDO2, CdoA, CdoB, cysteine dioxygenase, cysteine oxidase, Fe(II) cysteine dioxygenase, H16_A1614, H16_B1863, oxygenase, cysteine di-

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.20 cysteine dioxygenase

Activating Compound

Activating Compound on EC 1.13.11.20 - cysteine dioxygenase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-dipyridyl
-
slight activation at 0.01 mM
8-hydroxyquinoline
-
slight activation at 0.01 mM
Carboxyethyl-L-cysteine
-
at 10 mM, activation
carboxymethyl-L-cysteine
-
at 10 mM, activation
cysteamine
cysteine
-
protein expression of recombinant wild-type enzyme in HepG2/C3A cells increases by 160% when extracellular cysteine levels are increased from 0 to 1 mM cysteine
D-cysteine
-
at 10 mM, activation
diethyldithiocarbamate
-
without protein-A: 30% activation at 0.1 mM
DL-homocysteine
Fe2+
-
stimulates
hydrocortisone
-
induces
hydroxylamine
-
activates, restores the inhibition by Fe2+
L-cysteine
methionine
N-acetyl-L-cysteine
NAD(P)H
NAD+
-
stimulates
NADH
-
stimulates
Neocuproine
-
without protein-A: slight activation at 0.1 mM
S-methyl-L-cysteine
additional information
-