1.13.11.20: cysteine dioxygenase

This is an abbreviated version!
For detailed information about cysteine dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.20

1.13.11.20

taurine

sulfinic

non-heme

hypotaurine

cysteinesulfinate

cysteamine

cystathionine

3-mercaptopropionate

cys-tyr

taut

adenosyltransferase

desulfhydration

2-his-1-carboxylate

gamma-lyase

cupins

2-aminoethanethiol

medicine

Reaction

Synonyms

3-mercaptopropionate dioxygenase, 3MDO, ADO, Arg-type CDO, BsCDO, CDO, CDO1, CDO2, CdoA, CdoB, cysteine dioxygenase, cysteine dioxygenase type 1, cysteine oxidase, Fe(II) cysteine dioxygenase, H16_A1614, H16_B1863, NP_251292, oxygenase, cysteine di-, PA2602, PCO1, PCO4

ECTree

1 Oxidoreductases

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.13.11 With incorporation of two atoms of oxygen

1.13.11.20 cysteine dioxygenase

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Results	in table
42	Activating Compound
5409	AA Sequence
3	Application
1	CAS Registry Number
37	Cloned(Commentary)
11	Cofactor
15	Crystallization (Commentary)
131	Disease/ Diagnostics
5	Expression
64	General Information
1	General Stability
95	Inhibitors
16	kcat/KM [mM/s]
3	Ki Value [mM]
46	KM Value [mM]
5	Localization
63	Metals/Ions
26	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
114	Organism
3	Oxidation Stability
7	Pathway
85	PDB ID
24	pH Optimum
1	pH Range
4	pI Value
8	Posttranslational Modification
27	Protein Variants
32	Purification (Commentary)
10	Reaction
4	Reaction Type
104	Reference
65	Source Tissue
23	Specific Activity [micromol/min/mg]
4	Storage Stability
128	Substrates and Products (Substrate)
23	Subunits
85	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Range [°C]
31	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 1.13.11.20 - cysteine dioxygenase

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2,2'-dipyridyl

Rattus norvegicus

slight activation at 0.01 mM

439546

8-hydroxyquinoline

Rattus norvegicus

slight activation at 0.01 mM

439546

Carboxyethyl-L-cysteine

Rattus norvegicus

at 10 mM, activation

439542

carboxymethyl-L-cysteine

at 10 mM, activation

cysteamine

cysteine

protein expression of recombinant wild-type enzyme in HepG2/C3A cells increases by 160% when extracellular cysteine levels are increased from 0 to 1 mM cysteine

684337

D-cysteine

Rattus norvegicus

at 10 mM, activation

439542

diethyldithiocarbamate

Rattus norvegicus

without protein-A: 30% activation at 0.1 mM

DL-homocysteine

ethylxanthate

0.002 mM, 110% of initial activity, 0.004 mM, 89% of initial activity

Fe2+

stimulates

hydrocortisone

induces

hydroxylamine

activates, restores the inhibition by Fe2+

L-cysteine

methionine

N-acetyl-L-cysteine

NAD(P)H

NAD+

stimulates

NADH

Neocuproine

without protein-A: slight activation at 0.1 mM

439548

S-methyl-L-cysteine

2 entries

additional information

5 entries