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1.13.11.2: catechol 2,3-dioxygenase

This is an abbreviated version!
For detailed information about catechol 2,3-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.2

Reaction

catechol
+
O2
=
2-hydroxymuconate-6-semialdehyde

Synonyms

2,3-dihydroxybenzenesulfonate 2,3-dioxygenase, 3-sulfocatechol-2,3-dioxygenase, 3SC23O, A23O, AtdB, BupB, C2,3O, C23D, C23o, C23O-2G, C23O1, C23O2, C23Os, CatE, catechol 2,3 dioxygenase, catechol 2,3-di-2,3-pyrocatechase, catechol 2,3-dioxygenase, catechol 2,3-oxygenase, catechol oxygenase, catechol-2,3-dioxygenase, CbzE, CD-2,3, EC 1.13.1.2, ECDO, extradiol dioxygenase MhpB, Extradiol-cleaving catecholic dioxygenase, meta-cleavage dioxygenase, metapyrocatechase, More, oxygenase, PheB, pyrocatechol 2,3-dioxygenase, Saci_2295, SSO1223, SsoC2,3O, ssol_2912, tbuE, TdnC, TodE, XylE

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.2 catechol 2,3-dioxygenase

Oxidation Stability

Oxidation Stability on EC 1.13.11.2 - catechol 2,3-dioxygenase

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OXIDATION STABILITY
ORGANISM
UNIPROT
LITERATURE
25°C, half-life of 69 min in air, 37°C, half-life of 70 min in argon
-
680607
acetone protects almost completely against inactivation by air
addition of H2O2 to the enzyme completely destroyes activity
-
439584
ethanol protects against inactivation by air
-
439563
extremely sensitive to O2, easily inactivated in presence of air
like native enzyme the immobilized enzyme is rapidly inactivated by oxidants such as O2 or H2O2
-
439571
more than 95% of enzyme activity is lost after a 5-min exposure to equimolar H2O2
-
439590
significant nitrate-dependent enhanced degradation of toluene under hypoxic i.e. oxygen-limited condition