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1.13.11.2: catechol 2,3-dioxygenase

This is an abbreviated version!
For detailed information about catechol 2,3-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.2

Reaction

catechol
+
O2
=
2-hydroxymuconate-6-semialdehyde

Synonyms

2,3-dihydroxybenzenesulfonate 2,3-dioxygenase, 3-sulfocatechol-2,3-dioxygenase, 3SC23O, A23O, AtdB, BupB, C2,3O, C23D, C23o, C23O-2G, C23O1, C23O2, C23Os, CatE, catechol 2,3 dioxygenase, catechol 2,3-di-2,3-pyrocatechase, catechol 2,3-dioxygenase, catechol 2,3-oxygenase, catechol oxygenase, catechol-2,3-dioxygenase, CbzE, CD-2,3, EC 1.13.1.2, ECDO, extradiol dioxygenase MhpB, Extradiol-cleaving catecholic dioxygenase, meta-cleavage dioxygenase, metapyrocatechase, More, oxygenase, PheB, pyrocatechol 2,3-dioxygenase, Saci_2295, SSO1223, SsoC2,3O, ssol_2912, tbuE, TdnC, TodE, XylE

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.2 catechol 2,3-dioxygenase

Expression

Expression on EC 1.13.11.2 - catechol 2,3-dioxygenase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
by phenol and m-cresol
C23O activity (TodE) is almost completely abrogated by exposure to 0.2 mM 3-vinylcatechol
-
C23O activity (TodE) is is unaffected by styrene, toluene, and 3-methylcatechol
-
induced by naphthalene, biphenyl and pentachlorophenol
mRNA expression of C23O is increased in 2,4-dichlorophenol-amended soil
-
ssol_2912 is undetectable when the strain is harvested from the medium with glucose as the sole carbon source, it greatly increased when the strain is harvested from the media with phenol
the catDE operon is 13-60fold induced in response to quinone-like electrophiles (catechol and MHQ, 1 mM) and diamide in the wild type
the enzyme in strain KB2 is induced by growth on methylphenols
the enzyme is induced by growth on cadmium
when used as sole carbon sources benzoate and meta-toluate lead to elevated expression. The induction of xylE is the highest (at 93.5times higher than succinate grown cells) when grown on benzoate or meta-toluate
YodB and its paralog YvaP (CatR) are repressors of the yfiDE (catDE) operon encoding a catechol-2,3-dioxygenase