1.13.11.15: 3,4-dihydroxyphenylacetate 2,3-dioxygenase

This is an abbreviated version!
For detailed information about 3,4-dihydroxyphenylacetate 2,3-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.15

1.13.11.15

extradiol

catecholate

4-nitrocatechol

fuscum

brevibacterium

globiformis

manganese-dependent

ring-cleaving

extradiol-cleaving

second-sphere

monoanionic

hydroperoxo

4-hydroxyphenylacetate

superoxo

alkylperoxo

feiii-superoxo

manganeseii

ortho-dihydroxylated

side-on

crystallo

Reaction

2-hydroxy-5-carboxymethylmuconate semialdehyde

Synonyms

2,3-HPCD, 3,4-dihydroxyphenylacetic acid 2,3-dioxygenase, Bf 2,3-HPCD, DHPAO, Fe-HPCD, Fe-MndD, FeHPCD, homoprotocatechuate 2,3 dioxygenase, homoprotocatechuate 2,3-dioxygenase, homoprotocatechuate dioxygenase, HPADO, HPC 2,3-dioxygenase, HPC dioxygenase, HPCA 2,3-dioxygenase, HPCD, Mn(II)-dependent 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn-HPCD, Mn-MndD, MndD, MnHPCD, oxygenase, homoprotocatechuate 2,3-di-, PaDHPAO

ECTree

1 Oxidoreductases

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.13.11 With incorporation of two atoms of oxygen

1.13.11.15 3,4-dihydroxyphenylacetate 2,3-dioxygenase

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Results	in table
3	Activating Compound
2227	AA Sequence
2	Application
1	CAS Registry Number
8	Cloned(Commentary)
8	Crystallization (Commentary)
2	Expression
7	General Information
4	General Stability
46	Inhibitors
2	kcat/KM [mM/s]
9	Ki Value [mM]
40	KM Value [mM]
41	Metals/Ions
16	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
84	Organism
6	Pathway
72	PDB ID
18	pH Optimum
2	pH Range
2	pH Stability
29	Protein Variants
15	Purification (Commentary)
4	Reaction
3	Reaction Type
60	Reference
3	Source Tissue
8	Specific Activity [micromol/min/mg]
2	Storage Stability
102	Substrates and Products (Substrate)
14	Subunits
49	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
22	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 1.13.11.15 - 3,4-dihydroxyphenylacetate 2,3-dioxygenase

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102000

Klebsiella pneumoniae

gel filtration

439626

106000

Geobacillus stearothermophilus

gel filtration

439618

112200

Pseudomonas aeruginosa

recombinant enzyme, gel filtration

743618

120000

Brevibacillus brevis

equilibrium sedimentation

138000

gel filtration

140000

gel filtration

220000

Brevibacterium fuscum

equilibrium sedimentation

439623

25500

Klebsiella pneumoniae

4 * 25500, SDS-PAGE

439626

282000

Arthrobacter synephrinum

gel filtration

31000

x * 31000, SDS-PAGE

33000

gel filtration

35000

4 * 35000, SDS-PAGE

36000

4 * 36000, SDS-PAGE

42500