1.13.11.11: tryptophan 2,3-dioxygenase

This is an abbreviated version!
For detailed information about tryptophan 2,3-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.11

1.13.11.11

indoleamine

kynurenine

heme

quinolinic

n-formylkynurenine

l-trp

3-hydroxyanthranilate

2,3-dioxygenase-1

3-monooxygenase

aminocarboxymuconate-semialdehyde

3,4-dioxygenase

picolinic

heme-containing

tryptophan-degrading

drug development

medicine

3-hydroxykynurenine

tryptophan-catabolizing

Reaction

L-tryptophan

+

O2

=

N-formyl-L-kynurenine

Synonyms

33737, BRAFLDRAFT_210874, C28H8.11, hTDO, IDO-1, IDO-2, TDO, TDO2, TDOa, v1g157887, vCG5163, XcTDO

ECTree

1 Oxidoreductases

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.13.11 With incorporation of two atoms of oxygen

1.13.11.11 tryptophan 2,3-dioxygenase

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2

Activating Compound

6396

2

13

Cloned(Commentary)

10

2

Crystallization (Commentary)

288

Disease/ Diagnostics

12

29

General Information

20

26

25

1

4

21

Natural Substrates/ Products (Substrates)

20

8

65

9

3

Purification (Commentary)

3

25

34

39

Substrates and Products (Substrate)

6

28

1

Systematic Name

13

Temperature Optimum [°C]

7

Turnover Number [1/s]