1.12.98.4: sulfhydrogenase

This is an abbreviated version!
For detailed information about sulfhydrogenase, go to the full flat file.

Word Map on EC 1.12.98.4

Reaction

H2
+
(sulfide)n
=
hydrogen sulfide
+
(sulfide)n-1

Synonyms

H-II, H2:sulfuroxidoreductase complex, hydrogenase II, NiFe sulfhydrogenase, polysulfide dehydrogenase, polysulfide reductase, reductase, sulfur, SH2ase, sulfhydrogenase, sulfur reductase, sulhydrogenase

ECTree

     1 Oxidoreductases
         1.12 Acting on hydrogen as donor
             1.12.98 With other, known, physiological acceptors
                1.12.98.4 sulfhydrogenase

Systematic Name

Systematic Name on EC 1.12.98.4 - sulfhydrogenase

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SYSTEMATIC NAME
IUBMB Comments
H2:polysulfide oxidoreductase
An iron-sulfur protein. The enzyme from the hyperthermophilic archaeon Pyrococcus furiosus is part of two heterotetrameric complexes where the beta and gamma subunits function as sulfur reductase and the alpha and delta subunits function as hydrogenases (EC 1.12.1.3, hydrogen dehydrogenase [NADP+] and EC 1.12.1.4, hydrogen dehydrogenase [NAD(P)+], respectively). Sulfur can also be used as substrate, but since it is insoluble in aqueous solution and polysulfide is generated abiotically by the reaction of hydrogen sulfide and sulfur, polysulfide is believed to be the true substrate [2].