1.12.1.3: hydrogen dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about hydrogen dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.12.1.3

Reaction

H2
+
NADP+
=
H+
+
NADPH

Synonyms

hydrogenase [ambiguous], NADP-dependent hydrogenase, NADP-linked hydrogenase, NADP-reducing hydrogenase, NADPH-dependent hydrogenase I, NiFe-hydrogenase, SHI, soluble hydrogenase I, [NiFe]-hydrogenase

ECTree

     1 Oxidoreductases
         1.12 Acting on hydrogen as donor
             1.12.1 With NAD+ or NADP+ as acceptor
                1.12.1.3 hydrogen dehydrogenase (NADP+)

Systematic Name

Systematic Name on EC 1.12.1.3 - hydrogen dehydrogenase (NADP+)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SYSTEMATIC NAME
IUBMB Comments
hydrogen:NADP+ oxidoreductase
The protein from the bacterium Desulfovibrio fructosovorans is an iron-sulfur protein that exclusively functions as a hydrogen dehydrogenase [1], while the enzyme from the archaeon Pyrococcus furiosus is a nickel, iron, iron-sulfur protein, that is part of a heterotetrameric complex where the alpha and delta subunits function as a hydrogenase while the beta and gamma subunits function as sulfur reductase (EC 1.12.98.4, sulfhydrogenase). Different from EC 1.12.1.5, hydrogen dehydrogenase [NAD(P)+].