1.12.1.3: hydrogen dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about hydrogen dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.12.1.3

Reaction

H2
+
NADP+
=
H+
+
NADPH

Synonyms

hydrogenase [ambiguous], NADP-dependent hydrogenase, NADP-linked hydrogenase, NADP-reducing hydrogenase, NADPH-dependent hydrogenase I, NiFe-hydrogenase, SHI, soluble hydrogenase I, [NiFe]-hydrogenase

ECTree

     1 Oxidoreductases
         1.12 Acting on hydrogen as donor
             1.12.1 With NAD+ or NADP+ as acceptor
                1.12.1.3 hydrogen dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.12.1.3 - hydrogen dehydrogenase (NADP+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
H+ + NADPH
H2 + NADP+
show the reaction diagram
-
-
-
?
H+ + reduced benzyl viologen
H2 + oxidized benzyl viologen
show the reaction diagram
-
-
-
?
H2 + 2,6-dichlorophenolindophenol
H+ + ?
show the reaction diagram
-
-
-
r
H2 + NAD+
H+ + NADH
show the reaction diagram
specific activity with NAD+ as electron acceptor is 150times lower than that of NADP+
-
-
r
H2 + NADP+
H+ + NADPH
show the reaction diagram
H2 + oxidized benzyl viologen
H+ + reduced benzyl viologen
show the reaction diagram
H2 + oxidized ferredoxin
H+ + reduced ferredoxin
show the reaction diagram
-
-
-
?
H2 + oxidized methyl viologen
H+ + reduced methyl viologen
show the reaction diagram
H2 + oxidized methylene blue
H+ + reduced methylene blue
show the reaction diagram
-
-
-
r
NADPH + H+
H2 + NADP+
show the reaction diagram
-
-
-
?
additional information
?
-
-
the enzyme introduces corrosion of 316L stainless steel in the presence of NAD+. The enzyme induces the occurrence of cathodic and anodic microsites on the same electrode surface
-
-
-