1.11.2.2: myeloperoxidase
This is an abbreviated version!
For detailed information about myeloperoxidase, go to the full flat file.
Word Map on EC 1.11.2.2
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1.11.2.2
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neutrophil
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necrosis
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leukocyte
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tnf
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malondialdehyde
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dismutase
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colitis
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reperfusion
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pulmonary
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artery
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endothelial
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polymorphonuclear
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ischemia
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catalase
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monocyte
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sham
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bowel
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lps
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mucosal
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ulcer
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edema
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bronchoalveolar
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wistar
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granulocyte
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lavage
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lipopolysaccharide
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sod
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hypochlorous
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hocl
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vasculitis
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ischemia-reperfusion
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factor-alpha
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macroscopic
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tnf-alpha
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eosinophil
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elastase
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dextran
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ancas
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myeloid
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dss-induced
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degranulation
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glomerulonephritis
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lactoferrin
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icam-1
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granulomatosis
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antineutrophil
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instil
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medicine
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carrageenan-induced
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lactoperoxidase
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crescent
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analysis
- 1.11.2.2
- neutrophil
- necrosis
- leukocyte
- tnf
- malondialdehyde
- dismutase
- colitis
-
reperfusion
- pulmonary
- artery
- endothelial
-
polymorphonuclear
- ischemia
- catalase
- monocyte
-
sham
- bowel
- lps
- mucosal
- ulcer
- edema
-
bronchoalveolar
- wistar
- granulocyte
-
lavage
- lipopolysaccharide
- sod
-
hypochlorous
- hocl
- vasculitis
-
ischemia-reperfusion
- factor-alpha
-
macroscopic
- tnf-alpha
-
eosinophil
- elastase
- dextran
-
ancas
- myeloid
-
dss-induced
-
degranulation
- glomerulonephritis
- lactoferrin
- icam-1
- granulomatosis
-
antineutrophil
-
instil
- medicine
-
carrageenan-induced
- lactoperoxidase
-
crescent
- analysis
Reaction
Synonyms
donor, hydrogen peroxide oxidoreductase, donor, hydrogen peroxideoxidoreductase, donor: H2O2 oxidoreductase, donor:H2O2 oxidoreductase, donor:hydrogen peroxide oxidoreductase, donor:hydrogen-peroxide oxidoreductase, EC 1.11.1.7, epx2a, hemi-MPO, hemi-myeloperoxidase, LPO, MPO, MPX, myeloperoxidase, peroxinectin, properoxinectin, recombinant human MPO, rhMPO, tissue myeloperoxidase
ECTree
1.11.2.2 myeloperoxidaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 1.11.2.2 - myeloperoxidase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
Cl- + H2O2 + H+ + taurine + H+
taurine monochloroamine + 2 H2O
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the taurine chlorination reaction mediated by the myeloperoxidase system in vivo may involve an enzyme intermediate species rather than free HOCl
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-
?
thiocyanate + H2O2 + H+
hypothiocyanite + H2O
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thiocyanate is a major physiological substrate of myeloperoxidase and most favoured substrate compared to chloride and bromide
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-
?
Cl- + H2O2 + H+
HClO + H2O
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-
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?
I- + H2O2
?
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myeloperoxidase plays a fundamental role in oxidant production by neutrophils
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-
?
additional information
?
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myeloperoxidase kills microorganisms via a reaction that involves H2O2 and a halide
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?
additional information
?
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possible role of the enzyme for neutrophil myeloperoxidase in cystic fibrosis lung disease
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-
?
