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1.11.2.2: myeloperoxidase

This is an abbreviated version!
For detailed information about myeloperoxidase, go to the full flat file.

Word Map on EC 1.11.2.2

Reaction

Cl-
+
H2O2
+
H+
=
HClO
+
H2O

Synonyms

donor, hydrogen peroxide oxidoreductase, donor, hydrogen peroxideoxidoreductase, donor: H2O2 oxidoreductase, donor:H2O2 oxidoreductase, donor:hydrogen peroxide oxidoreductase, donor:hydrogen-peroxide oxidoreductase, EC 1.11.1.7, epx2a, hemi-MPO, hemi-myeloperoxidase, LPO, MPO, MPX, myeloperoxidase, peroxinectin, properoxinectin, recombinant human MPO, rhMPO, tissue myeloperoxidase

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.2 Peroxygenases
                1.11.2.2 myeloperoxidase

KM Value

KM Value on EC 1.11.2.2 - myeloperoxidase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.016 - 0.039
1-acetyl-4-(methylsulfanyl)benzene
0.027 - 0.067
1-chloro-4-(methylsulfanyl)benzene
0.012 - 0.03
1-methoxy-4-(methylsulfanyl)benzene
0.032 - 0.04
1-methyl-4-(methylsulfanyl)benzene
0.066 - 0.076
1-nitro-4-(methylsulfanyl)benzene
0.031
10-acetyl-3,7-dihydroxyphenoxazine
at pH 5.6 and 25°C
0.52 - 21.9
3,4-dihydroxyphenylacetic acid
0.057 - 0.104
4-(methylsulfanyl)aniline
0.072 - 0.081
benzothiophene
0.05 - 0.083
benzyl methyl sulfide
2
Br-
-
in 100 mM phosphate buffer, pH 7.4, at 21°C
1.84 - 21.1
catechol
0.089
Chloroacetonitrile
-
at pH 5.5, 37°C, 0.1 mM KCl, 0.5 mM H2O2, 0.15 mM chloroacetonitrile, 5 units/ml MPO, and 0.25 mM NaOCl during an incubation period of 60 min
175
Cl-
-
in 100 mM phosphate buffer, pH 7.4, at 21°C
0.64 - 136.3
dopamine
0.03 - 0.07
H2O2
0.026 - 0.041
phenyl propan-2-yl sulfide
0.25 - 0.29
SCN-
0.018 - 0.02
thioanisole
0.5
thiocyanate
-
in 100 mM phosphate buffer, pH 7.4, at 21°C