1.11.1.B7: bromide peroxidase (heme-containing)
This is an abbreviated version!
For detailed information about bromide peroxidase (heme-containing), go to the full flat file.
Reaction
Synonyms
DdPoxA, heme peroxidase, More, peroxinectin A
ECTree
1.11.1.B7 bromide peroxidase (heme-containing)Advanced search results
results (
results (General Information
General Information on EC 1.11.1.B7 - bromide peroxidase (heme-containing)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
GENERAL INFORMATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
evolution
DdPoxA is a member of the peroxidase-cyclooxygenase superfamily, family 6. Phylogenetic reconstruction of the main evolutionary lines of the mammalian heme peroxidases such as lactoperoxidase or myeloperoxidase reveals the presence of other bacterial and early eukaryotic representatives within family 6 of the peroxidase-cyclooxygenase superfamily
malfunction
the DELTADdpoxA mutant has significant deficiencies in keeping the slug and the sori sterile upon cell development
additional information
active site architecture analysis and comparison, e.g. to lactoperoxidase (LPO). DdPoxA has only one covalent link between the 1-methyl substituent of the prosthetic group and Glu236 because the DdPoxA residue corresponding to Asp-225 of LPO is an isoleucine. The important catalytic residues on the distal heme site (His101, Gln97, and Arg233) are fully conserved, including Glu236 that forms an ester bond with the 1-methyl substituent of the heme porphyrin ring
