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1.11.1.9: glutathione peroxidase

This is an abbreviated version!
For detailed information about glutathione peroxidase, go to the full flat file.

Word Map on EC 1.11.1.9

Reaction

2 glutathione +

H2O2
=
glutathione disulfide
+ 2 H2O

Synonyms

2-SeCD, 3,3'-telluro-bis(proapne-3,1-diyl)adamantane carboxylate, 6P229, ADA-Te-OH, ARMEP24, AtGPX1, ATGPX3, c-GPx4, Cellular glutathione peroxidase, cgd3_460, cGPx, Cuticular glycoprotein GP29, DI29, ebselen, EGLP, Epididymis-specific glutathione peroxidase-like protein, Extracellular glutathione peroxidase, G-6137, Gastrointestinal glutathione peroxidase, glutathione peroxidase 1, glutathione peroxidase 2, glutathione peroxidase 3, glutathione peroxidase 4, glutathione peroxidase Gpx2, glutathione peroxidase Gpx3, glutathione peroxidase-1, glutathione peroxidase-2, glutathione peroxidase-3, glutathione peroxidase-4, glutathione-dependent peroxidase I, glutathione:hydrogen-peroxide oxidoreductase, GP30, GPRP, GPX, Gpx-1, GPx-2, GPx-3, GPx-4, GPx-5, GPx-6, GPx-7, GPx-8, GPX1, Gpx2, GPX3, GPx4, GPX5, GSH peroxidase, GSH-Px, GSHPx, GSHPx-GI, intracellular GpX, m-GPx4, Major androgen-regulated protein, Major surface antigen GP29, n-GPx4, Nt-SubC08, Odorant-metabolizing protein RY2D1, Os02g0664000, OsGPX5, peroxidase, glutathione, PGdx, pGPx, PHGPX, phospholipid glutathione peroxidase, phospholipid hydroperoxide glutathione peroxidase, phospholipid hydroperoxide glutathione peroxidase, nuclear form, phospholipid hydroperoxide Gpx, plasma glutathione peroxidase, prion protein Ure2, reduced glutathione peroxidase, Salt-associated protein, Se-GPx, Se-hGSTZ1-1, Se-scFv-B3, secreted GpX, SeGPx, selenium containing glutathione transferase zeta1-1, selenium-dependent glutathione peroxidase, selenium-glutathione peroxidase, seleno-dependent glutathione peroxidase 1, selenosubtilisin, snGPx, TcGPXI, TTHERM_00046090, TTHERM_00046110, TTHERM_01099010, Ure2

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.9 glutathione peroxidase

Purification

Purification on EC 1.11.1.9 - glutathione peroxidase

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
ammonium sulfate precipitation and Mono P HR 5/20 column chromatography
-
by dialysis (20 kDa membrane cutoff), gel-filtration and ion-exchange chromatography
-
by ethanol-chloroform treatment, acetone precipitation and ion exchange chromatography
-
DEAE-cellulose column chromatography, Sephadex G-25 gel filtration, and Toyopearl HW-65 column chromatography
-
glutathione-Sepharose column chromatography and HiTrap SP FF column chromatography
Ni-NTA resin column chromatography and Superdex 75 gel filtration
nickel-agarose column chromatography
-
oxidized and reduced form
-
Superdex 75 gel filtration and DEAE column chromatography