1.11.1.7: peroxidase

This is an abbreviated version!
For detailed information about peroxidase, go to the full flat file.

Reaction

2 phenolic donor +

Synonyms

acidic peroxidase, acidic POD, ALSP, AnaPX, anionic isoperoxidase, anionic peroxidase A1, AOPTP, basic peroxidase, basic POD, BCcP, black radish peroxidase A, black radish peroxidase B, BRP-A, BRP-B, cationic peroxidase, cationic peroxidase Cs, class III plant peroxidase, CmMnP, constitutive peroxidase, CP, cPOD-I, CYP119, dehaloperoxidase A, dehaloperoxidase B, DHP A, donor: H2O2 oxidoreductase, donor: hydrogen peroxide oxidoreductase, donor:hydrogen peroxide oxidoreductase, DtpA, ECPOX, ECPOX 1, ECPOX 2, ECPOX 3, ELP, eosinophil peroxidase, EPO, extensin peroxidase, extracellular peroxidase, FP1, Fp2, FP3, GCP1, GCP2, guaiacol peroxidase, H2O2 oxidoreductase, Hb peroxidase, Hb1, heme peroxidase, hemoglobin 1, hemoglobin peroxidase, hexacoordinate (class 1) non-symbiotic hemoglobin, horseradisch peroxidase, horseradish peroxidase, horseradish peroxidase (HRP), horseradish peroxidase C, HP, HRP, HRP A2, HRP C1A, HRP-C, HRPC, HRPO, HRP_A2A, HRP_C1A, HRP_E5, HTHP, hydrogen donor oxidoreductase, Japanese radish peroxidase, lactoperoxidase, LPO, LPRX, LPS, MAP-2744c, MGP, MnP124076, MnP13, More, MPO, myeloperoxidase, neutral peroxidase, neutral POD, NGO_0994, nsHb-1, oxyperoxidase, p20, PA1, PerII, peroxidase, peroxidase isoenzyme E5, POC1, POD, POD1, POII, POX, POX I, POX II, POX2, protoheme peroxidase, Prx02, Prx03, Prx06, Prx07, Prx09, Prx1, Prx11, Prx114, Prx12, Prx13, Prx15, Prx17, Prx21, Prx22, Prx27, Prx28, Prx30, Prx31, Prx32, Prx33, Prx34, Prx36, Prx37, Prx39, Prx42, Prx43, Prx45, Prx49, Prx50, Prx51, Prx52, Prx53, Prx55, Prx56, Prx57, Prx58, Prx59, Prx60, Prx62, Prx64, Prx66, Prx67, Prx68, Prx69, Prx70, Prx71, Prx72, Prx73, pyrocatechol peroxidase, QPO, quinol peroxidase, rhEPO, rHRP1, rHRP2, royal palm tree peroxidase, rPOD-II, RPTP, rubrerythrin, SacD, Saci_2081, SBP, scavengase, scopoletin peroxidase, SfmD, short PMnP, SPC4, Ssp, stigma-specific peroxidase, thiocyanate peroxidase, thiol peroxidase, TOP, TP I, Tpx, tyrosine-coordinated heme protein, vacuolar class III peroxidase, vascular peroxidase 1, verdoperoxidase, versatile peroxidase, versatile peroxidase VPL2, VP, VPO1, VPO2, WPTP

ECTree

     1 Oxidoreductases

         1.11 Acting on a peroxide as acceptor

             1.11.1 Peroxidases

                1.11.1.7 peroxidase

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Results	in table
25	Activating Compound
25544	AA Sequence
24	Application
1	CAS Registry Number
25	Cloned(Commentary)
66	Cofactor
14	Crystallization (Commentary)
4636	Disease/ Diagnostics
5	Expression
9	General Information
16	General Stability
43	IC50 Value
288	Inhibitors
25	kcat/KM [mM/s]
9	Ki Value [mM]
337	KM Value [mM]
30	Localization
75	Metals/Ions
126	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
18	Organic Solvent Stability
254	Organism
2	Oxidation Stability
12	Pathway
226	PDB ID
106	pH Optimum
26	pH Range
32	pH Stability
27	pI Value
37	Posttranslational Modification
48	Protein Variants
105	Purification (Commentary)
3	Reaction
4	Reaction Type
241	Reference
2	Renatured (Commentary)
150	Source Tissue
75	Specific Activity [micromol/min/mg]
13	Storage Stability
678	Substrates and Products (Substrate)
69	Subunits
323	Synonyms
1	Systematic Name
56	Temperature Optimum [°C]
14	Temperature Range [°C]
93	Temperature Stability [°C]
97	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 1.11.1.7 - peroxidase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0009

1-(5-fluoro-1H-indol-3-yl)methanamine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00175

1-methyl-L-tryptophan

Homo sapiens

-

at 25°C in 0.2 M sodium phosphate buffer, pH 7.0

712063

0.00009

2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.0002

2-(5-fluoro-1H-indol-3-yl)-N-methylethanamine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00013

3-(5-fluoro-1H-indol-3-yl)-N,N-dimethylpropan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.0002

3-(5-fluoro-1H-indol-3-yl)-N-methylpropan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00017

3-(5-fluoro-1H-indol-3-yl)-N-propylpropan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00005

3-(5-fluoro-1H-indol-3-yl)propan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.000015

4-(5-fluoro-1H-indol-3-yl)butan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.848

4-aminobenzenesulfanilamide

Bos taurus

-

at pH 6.0 and 22°C

725055

1.05

4-aminobenzohydrazide

Brassica oleracea var. capitata f. rubra

-

pH 6.0, 25°C

741639

0.000008

5-(5-fluoro-1H-indol-3-yl)pentan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.001

5-fluoro-3-[(4-methylpiperazin-1-yl)methyl]-1H-indole

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.0002

5-fluoro-3-[2-(4-methylpiperazin-1-yl)ethyl]-1H-indole

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00004

5-fluoro-3-[2-(pyrrolidin-1-yl)ethyl]-1H-indole

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00035

5-fluoro-3-[3-(4-methylpiperazin-1-yl)propyl]-1H-indole

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00032

5-fluoro-3-[3-(pyrrolidin-1-yl)propyl]-1H-indol

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00325

5-fluoro-L-tryptophan

Homo sapiens

-

at 25°C in 0.2 M sodium phosphate buffer, pH 7.0

712063

0.0002

5-fluorotryptamine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00576

5-methyl-2-thiouracil

Bos taurus

-

-

698271

0.00885

5-n-propyl-2-thiouracil

Bos taurus

-

-

698271

0.00026

6-(5-fluoro-1H-indol-3-yl)hexan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.0853

9-methylanthracene

Armoracia rusticana

-

native HRP

696500

0.00951

captopril

Bos taurus

-

-

698271

10.49 - 3610

D-fructose

2 entries

710 - 2110

D-glucose

2 entries

0.0986

fluoranthene

Armoracia rusticana

-

native HRP

696500

0.00225

L-tryptophan

Homo sapiens

-

at 25°C in 0.2 M sodium phosphate buffer, pH 7.0

712063

0.000175

L-tryptophan benzyl ester

Homo sapiens

-

at 25°C in 0.2 M sodium phosphate buffer, pH 7.0

712063

0.00274

Methimazole

Bos taurus

-

-

698271

0.00016

N,N-diethyl-2-(5-fluoro-1H-indol-3-yl)ethanamine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00035

N,N-diethyl-3-(5-fluoro-1H-indol-3-yl)propan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.0003

N-ethyl-2-(5-fluoro-1H-indol-3-yl)ethanamine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.0003

N-ethyl-3-(5-fluoro-1H-indol-3-yl)propan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.0002

N-ethyl-N-[(5-fluoro-1H-indol-3-yl)methyl]ethanamine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00103

N-[2-(5-fluoro-1H-indol-3-yl)ethyl]butan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.0008

N-[2-(5-fluoro-1H-indol-3-yl)ethyl]propan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.0015

N-[3-(5-fluoro-1H-indol-3-yl)propyl]butan-1-amine

Homo sapiens

-

in phosphate buffer pH 7.4, at 37°C

712714

0.00035

Nalpha-methoxycarbonyl-L-tryptophan methyl ester

Homo sapiens

-

at 25°C in 0.2 M sodium phosphate buffer, pH 7.0

712063

0.0052

Nalpha-methyl-L-tryptophan

Homo sapiens

-

at 25°C in 0.2 M sodium phosphate buffer, pH 7.0

712063

0.01597

propofol

Bos taurus

-

at 25°C, pH 6.0

713470

10.49

D-fructose

Fragaria x ananassa

-

at 25°C

687230

3610

D-fructose

Fragaria vesca

-

at 25°C

687230

710

D-glucose

Cucumis melo var. cantalupo

-

at pH 7.0 and 25°C

687246

2110

D-glucose

Cucumis melo var. inodorus

-

at pH 7.0 and 25°C

687246