Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.11.1.29: mycoredoxin-dependent peroxiredoxin

This is an abbreviated version!
For detailed information about mycoredoxin-dependent peroxiredoxin, go to the full flat file.

Word Map on EC 1.11.1.29

Reaction

mycoredoxin
+
ROOH
=
mycoredoxin disulfide
 +
H2O
 +
ROH

Synonyms

AhpE, alkyl hydroperoxide reductase E, alkyl hydroxyperoxide reductase E, EC 1.11.1.15, mycothiol/mycoredoxin-1-dependent peroxidase, peroxiredoxin AhpE, Rv2238c

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.29 mycoredoxin-dependent peroxiredoxin

Natural Substrates Products

Natural Substrates Products on EC 1.11.1.29 - mycoredoxin-dependent peroxiredoxin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
hydrogen sulfide + ROOH
?
show the reaction diagram
-
-
-
-
?
mycoredoxin + ROOH
mycoredoxin disulfide + H2O + ROH
show the reaction diagram
-
Mycobacteria employ a versatile machinery of the mycothiol-dependent system, containing the proteins mycothiol disulfide reductase, the oxido-reductase Mycoredoxin-1 and the alkyl-hydroperoxide subunit E (AhpE). The mycothiol-dependent protein ensemble regulates the balance of oxidized-reduced mycothiol, to ensure a reductive intracellular environment for optimal functioning of its proteins even upon exposure to oxidative stress. The epitopes of MtMrx-1 and MtAhpE interaction are described
-
-
?
mycoredoxin-1 + ROOH
mycoredoxin-1 disulfide + H2O + ROH
show the reaction diagram
mycothiol + ROOH
?
show the reaction diagram
-
-
-
-
?
mycothiol + ROOH
mycothiol disulfide + H2O + ROH
show the reaction diagram