1.11.1.21: catalase-peroxidase
This is an abbreviated version!
For detailed information about catalase-peroxidase, go to the full flat file.
Word Map on EC 1.11.1.21
-
1.11.1.21
-
1.11.1.7
-
katgs
-
mycobacterium
-
tuberculosis
-
isoniazid
-
dismutase
-
ascorbate
-
heme
-
horseradish
-
peroxidases
-
guaiacol
-
ferric
-
myeloperoxidase
-
catalases
-
1.6.4.2
-
lignification
-
monofunctional
-
lactoperoxidase
-
peroxidatic
-
isonicotinic
-
high-spin
-
inh-resistant
-
isoniazid-resistant
-
o-dianisidine
-
pseudomallei
-
antituberculosis
-
soret
-
catalatic
-
pro-drug
-
antitubercular
-
medicine
-
mycolic
-
isoperoxidase
-
monodehydroascorbate
-
1.8.5.1
-
low-spin
-
1.10.3.1
-
pyrogallol
-
3-amino-1,2,4-triazole
-
coniferyl
-
1.14.18.1
-
4.3.1.5
-
synthesis
- 1.11.1.21
-
1.11.1.7
-
katgs
- mycobacterium
- tuberculosis
- isoniazid
- dismutase
- ascorbate
- heme
- horseradish
- peroxidases
- guaiacol
-
ferric
- myeloperoxidase
- catalases
-
1.6.4.2
-
lignification
-
monofunctional
- lactoperoxidase
-
peroxidatic
-
isonicotinic
-
high-spin
-
inh-resistant
-
isoniazid-resistant
- o-dianisidine
- pseudomallei
-
antituberculosis
-
soret
-
catalatic
-
pro-drug
-
antitubercular
- medicine
-
mycolic
-
isoperoxidase
- monodehydroascorbate
-
1.8.5.1
-
low-spin
-
1.10.3.1
- pyrogallol
- 3-amino-1,2,4-triazole
-
coniferyl
-
1.14.18.1
-
4.3.1.5
- synthesis
Reaction
2 H2O2
=
Synonyms
AfKatG, BW16_04845, CAT, CAT-2, catalase -peroxidase KatG, catalase peroxidase, catalase-peroxidase, catalase/peroxidase, CP 2, CP01, CP02, CPX, CthediskatG, EC 1.11.1.7, FeSOD A, FvCP01, FvCP02, FVEG_10866, FVEG_12888, HCP, hemoprotein b-590, HPI, hydroperoxidase I, KatG, KatG1, KatG2, KatP, katX2, KpCP, PCP, Rv1908c
ECTree
1.11.1.21 catalase-peroxidaseAdvanced search results
results (
results (KM Value
KM Value on EC 1.11.1.21 - catalase-peroxidase
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.23
NADH
-
peroxidatic activity, in 50 mM phosphate buffer, pH 7.0, at 25°C
0.17
NADPH
-
peroxidatic activity, in 50 mM phosphate buffer, pH 7.0, at 25°C
0.0055
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
mutant enzyme R108A/W111F/D141A, peroxidase activity, at pH 4.5 and 25°C
0.007
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase reaction, at pH 4.3 and 25°C
0.0092
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
mutant enzyme D141N, peroxidase activity, at pH 4.5 and 25°C
0.012
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, mutant enzyme KatGDELTAFG, in 50 mM acetate buffer pH 5.0, at 23°C
0.016
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase reaction, at pH 4.5 and 25°C
0.016
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase reaction, at pH 5.0 and 25°C
0.023
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme E291K, at pH 5.0 and 23°C
0.024
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
mutant enzyme R108A/W111F, peroxidase activity, at pH 4.5 and 25°C
0.024
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase reaction, at pH 4.3 and 25°C
0.028
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme E291K/E292A, at pH 5.0 and 23°C
0.03
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
mutant enzyme D141A, peroxidase activity, at pH 4.5 and 25°C
0.031
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase reaction, at pH 4.0 and 25°C
0.037
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme I290A/Q293A, at pH 5.0 and 23°C
0.043
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant Y22F, pH 5.0, 23°C
0.048
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, mutant enzyme R102L, at pH 6.0 and 25°C
0.05
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme Q293E, at pH 5.0 and 23°C
0.055
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, wild type enzyme, at pH 6.0 and 25°C
0.061
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme Y111A, peroxidase activity, in 50 mM acetate buffer, pH 5.0, 23°C
0.067
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase reaction, at pH 4.8 and 25°C
0.07
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
mutant enzyme D141E, peroxidase activity, at pH 4.5 and 25°C
0.07
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
mutant enzyme R108A/D141A, peroxidase activity, at pH 4.5 and 25°C
0.071
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme E291A, at pH 5.0 and 23°C
0.08
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, mutant enzyme H106C, at pH 6.0 and 25°C
0.08
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme Q293A, at pH 5.0 and 23°C
0.081
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme I290V/Q293V, at pH 5.0 and 23°C
0.086
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant DELTA200-214, pH 5.0, 23°C
0.087
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
wild type enzyme, peroxidase activity, in 50 mM acetate buffer, pH 5.0, 23°C
0.087
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
wild type enzyme, at pH 5.0 and 23°C
0.09
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme Q293V, at pH 5.0 and 23°C
0.1
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, mutant enzyme R102C, at pH 6.0 and 25°C
0.11
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidatic activity, in 50 mM phosphate buffer, pH 7.0, at 25°C
0.11
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidatic activity, wild type enzyme, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
0.13
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme I290V, at pH 5.0 and 23°C
0.14
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
wild type enzyme, peroxidase activity, at pH 4.5 and 25°C
0.16
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant enzyme I290A, at pH 5.0 and 23°C
0.23
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, wild type enzyme, in 50 mM acetate buffer pH 5.0, at 23°C
0.24
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, mutant enzyme W105L, at pH 6.0 and 25°C
0.3
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase reaction, at pH 4.5 and 25°C
0.31
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
wild-type, pH 5.0, 23°C
0.32
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidatic activity, mutant enzyme W107F/W321F, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
0.33
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, mutant enzyme H106Y, at pH 6.0 and 25°C
0.36
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidatic activity, mutant enzyme W321F, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
0.4
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, mutant enzyme R102K, at pH 6.0 and 25°C
0.41
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
mutant enzyme R108A, peroxidase activity, at pH 4.5 and 25°C
0.47
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidatic activity, mutant enzyme W107F, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
0.48
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidase activity, mutant enzyme W105F, at pH 6.0 and 25°C
0.55
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
mutant enzyme R108K, peroxidase activity, at pH 4.5 and 25°C
0.83
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
pH 5.0, 23°C
0.96
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidatic activity, using tert-butyl hydroperoxide as cosubstrate, in 10 mM K2HPO4/KH2PO4 (pH 7.5), at 25°C
1.06
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant DELTAL193-N228, pH 5.0, 23°C
1.2
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant DELTA209-228, pH 5.0, 23°C
1.2
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant E695A/Y697A, pH 7.0, 23°C
1.6
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
peroxidatic activity, mutant enzyme H108L, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
1.9
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant Y697A, pH 7.0, 23°C
2.2
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant L690A/R691A/E695A/Y697A, pH 7.0, 23°C
2.4
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
wild-type, N- and C-terminal domain separately expressed, pH 7.0, 23°C
2.7
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant L690A/R691A, pH 7.0, 23°C
2.7
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant R691A, pH 7.0, 23°C
2.9
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant E695A, pH 7.0, 23°C
3
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
in 50 mM acetate buffer, pH 5.0, at 23°C
3.3
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant L690A/R691A, N- and C-terminal domain separately expressed, pH 7.0, 23°C
3.6
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant E695A, N- and C-terminal domain separately expressed, pH 7.0, 23°C
4
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant R691A, N- and C-terminal domain separately expressed, pH 7.0, 23°C
4.5
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
wild-type, pH 7.0, 23°C
6
2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)
-
mutant Y697A, N- and C-terminal domain separately expressed, pH 7.0, 23°C
0.07
H2O2
-
mutant enzyme S315T, catalase activity, in 50 mM sodium phosphate buffer (pH 7.5), at 37°C
0.07
H2O2
-
mutant enzyme Y111A, peroxidase activity, in 50 mM acetate buffer, pH 5.0, 23°C
0.07
H2O2
-
wild type enzyme, catalase activity, in 50 mM sodium phosphate buffer (pH 7.5), at 37°C
0.09
H2O2
mutant enzyme D141N, peroxidase activity, at pH 4.5 and 25°C
0.12
H2O2
mutant enzyme D141E, peroxidase activity, at pH 4.5 and 25°C
0.14
H2O2
-
peroxidase activity, in 50 mM potassium phosphate containing 2 M NaCl, pH 7.5, at 25°C
0.18
H2O2
-
wild type enzyme, peroxidase activity, in 50 mM acetate buffer, pH 5.0, 23°C
0.19
H2O2
mutant enzyme D141A, peroxidase activity, at pH 4.5 and 25°C
0.27
H2O2
mutant enzyme R108A/D141A, peroxidase activity, at pH 4.5 and 25°C
0.31
H2O2
wild type enzyme, peroxidase activity, at pH 4.5 and 25°C
0.5
H2O2
mutant enzyme R108A, peroxidase activity, at pH 4.5 and 25°C
0.56
H2O2
mutant enzyme R108A/W111F, peroxidase activity, at pH 4.5 and 25°C
0.6
H2O2
-
catalatic activity, in 50 mM phosphate buffer, pH 7.0, at 25°C
0.83
H2O2
-
peroxidase activity, wild type enzyme, in 50 mM acetate buffer pH 5.0, at 23°C
0.85
H2O2
peroxidase activity, 50 mM potassium phosphate/sodium citrate buffer, pH 4.5, at 80°C
0.92
H2O2
mutant enzyme R108A/W111F/D141A, peroxidase activity, at pH 4.5 and 25°C
0.98
H2O2
mutant enzyme R108K, peroxidase activity, at pH 4.5 and 25°C
1.47
H2O2
-
peroxidase activity, in 50 mM potassium phosphate buffer (pH 7.0), at 30°C
1.5
H2O2
-
peroxidase activity, mutant enzyme KatGDELTAFG, in 50 mM acetate buffer pH 5.0, at 23°C
1.7
H2O2
-
catalase activity, mutant enzyme N153A, in 50 mM phosphate buffer, pH 7.0, and 30°C
2.3
H2O2
-
catalase activity, mutant enzyme N153D, in 50 mM phosphate buffer, pH 7.0, and 30°C
2.8
H2O2
wild type enzyme, in 25 mM HEPES-NaOH buffer (pH 7.0) at 25°C
3.03
H2O2
mutant C55A, pH not specified in the publication, temperature not specified in the publication
3.21
H2O2
mutant C55A/C74A, pH not specified in the publication, temperature not specified in the publication
3.5
H2O2
-
wild type enzyme, catalase activity, in 100 mM phosphate buffer, pH 7.0, 23°C
3.52
H2O2
mutant C26A/C74A, pH not specified in the publication, temperature not specified in the publication
3.66
H2O2
mutant C74A, pH not specified in the publication, temperature not specified in the publication
3.7
H2O2
-
catalase activity, in 50 mM potassium phosphate containing 2 M NaCl, pH 6.5, at 25°C
3.7
H2O2
wild type enzyme, catalase activity, at pH 7.0 and 37°C
3.84
H2O2
wild-type, pH not specified in the publication, temperature not specified in the publication
4
H2O2
-
catalase activity, wild type enzyme, 100 mM phosphate buffer pH 7.0, at 23°C
4.1
H2O2
-
catalase activity, wild type enzyme, in 50 mM phosphate buffer, pH 7.0, and 30°C
4.3
H2O2
-
catalase activity, in 67 mM phosphate buffer (pH 7.0), at 25°C
4.5
H2O2
-
catalase activity, mutant enzyme KatGDELTAFG, 100 mM phosphate buffer pH 7.0, at 23°C
5.18
H2O2
-
wild type enzyme, catalase activity, in 50 mM Na2HPO4, pH 7.0, 25°C
5.2
H2O2
-
mutant enzyme Y111A, catalase activity, in 100 mM phosphate buffer, pH 7.0, 23°C
6.16
H2O2
-
mutant enzyme R463L, catalase activity, in 50 mM Na2HPO4, pH 7.0, 25°C
6.3
H2O2
-
catalase activity, in 50 mM potassium phosphate buffer (pH 7.0), at 30°C
6.7
H2O2
-
catalase activity, pH and temperature not specified in the publication
13
H2O2
mutant enzyme R108A, catalase activity, at pH 7.0 and 37°C
24
H2O2
-
catalase activity, in 20 mM Tris-HCl buffer (pH 9.0), at 30°C
30
H2O2
-
catalatic activity, in 10 mM K2HPO4/KH2PO4 (pH 7.5), at 25°C
31.5
H2O2
-
catalatic activity, mutant enzyme W107F, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
32
H2O2
mutant enzyme R108A/D141A, catalase activity, at pH 7.0 and 37°C
32.1
H2O2
-
catalatic activity, mutant enzyme W321F, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
33
H2O2
-
catalatic activity, mutant enzyme W107F/W321F, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
35
H2O2
mutant enzyme R108A/W111F/D141A, catalase activity, at pH 7.0 and 37°C
36
H2O2
mutant enzyme R108A/W111F, catalase activity, at pH 7.0 and 37°C
42.6
H2O2
-
catalatic activity, wild type enzyme, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
54.9
H2O2
-
catalatic activity, mutant enzyme H108L, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
60
H2O2
mutant enzyme D141A, catalase activity, at pH 7.0 and 37°C
75
H2O2
mutant enzyme D141E, catalase activity, at pH 7.0 and 37°C
95
H2O2
mutant enzyme D141N, catalase activity, at pH 7.0 and 37°C
180
H2O2
mutant enzyme R108K, catalase activity, at pH 7.0 and 37°C
0.08
isoniazid
-
mutant enzyme S315T, in 50 mM sodium phosphate buffer (pH 7.5), at 37°C
0.43
isoniazid
-
wild type enzyme, in 50 mM sodium phosphate buffer (pH 7.5), at 37°C
0.0478
o-Dianisidine
-
peroxidase activity, in 50 mM potassium phosphate buffer (pH 7.0), at 30°C
0.14
o-Dianisidine
-
peroxidatic activity, with hydrogen peroxide as cosubstrate, in 50 mM phosphate buffer, pH 7.0, at 25°C
0.14
o-Dianisidine
-
peroxidatic activity, with tert-butyl hydroperoxide as cosubstrate, in 50 mM phosphate buffer, pH 7.0, at 25°C
0.31
pyrogallol
-
peroxidatic activity, in 50 mM phosphate buffer, pH 7.0, at 25°C
5.7
tert-butyl hydroperoxide
-
peroxidatic activity, mutant enzyme W107F, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
12.7
tert-butyl hydroperoxide
-
peroxidatic activity, mutant enzyme H108L, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
15.5
tert-butyl hydroperoxide
-
peroxidatic activity, mutant enzyme W107F/W321F, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
91.2
tert-butyl hydroperoxide
-
peroxidatic activity, mutant enzyme W321F, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
97.9
tert-butyl hydroperoxide
-
peroxidatic activity, wild type enzyme, in 10 mM KH2PO4/K2HPO4, pH 6.0, at 25°C
additional information
additional information
Michaelis-Menten kinetics
-
additional information
additional information
-
Michaelis-Menten kinetics
-
additional information
additional information
-
steady- and transient-state kinetics
-
