1.11.1.13: manganese peroxidase

This is an abbreviated version!
For detailed information about manganese peroxidase, go to the full flat file.

Word Map on EC 1.11.1.13

Reaction

2 Mn(II) + 2 H+ +

H2O2
= 2 Mn(III) + 2 H2O

Synonyms

hybrid Mn-peroxidase, L-MnP, LeMnP2, manganese peroxidase, manganese-dependent peroxidase, Mn-dependent (NADH-oxidizing) peroxidase, Mn2+: hydrogen peroxide oxidoreductase, Mn2+:hydrogen peroxide oxidoreductase, MnP, MnP 1, MnP II, MnP-GY, MnP-PGY, mnp1, MnP2, MnP3, MnP6, MP, multifunctional manganese peroxidase, Nf b19 MNP2, peroxidase, manganese, peroxidase-M2

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.13 manganese peroxidase

pH Stability

pH Stability on EC 1.11.1.13 - manganese peroxidase

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pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10
-
enzyme loses activity rapidly at pH 10
439841
2.5
-
25°C, 2 h, about 50% loss of activity
660342
3
-
25°C, 2 h, about 40% loss of activity
660342
3 - 6
-
stable
394600
3.5 - 5.5
-
the enzyme shows a half-life of 8.8 h at pH 3.5, the half-lives of MnP activity at pH 4.5, 5.0, and 5.5 are 89.5, 99, and 101 h, respectively
699016
4
-
half-life: 19 h
686451
4.5 - 6
-
25°C, 2 h, stable
660342
5
-
half-life: 23 h
686451
6.5
-
25°C, 2 h, about 20% loss of activity
660342
8
-
recombinant MnP: inactivation within 1 min, native MnP: inactivation within 15 min, A48C/A63C double mutant MnP: 1 h, 80% loss of activity
439853
additional information