1.11.1.12: phospholipid-hydroperoxide glutathione peroxidase

This is an abbreviated version!
For detailed information about phospholipid-hydroperoxide glutathione peroxidase, go to the full flat file.

Word Map on EC 1.11.1.12

Reaction

2 glutathione +

a hydroperoxy-fatty-acyl-[lipid]
=
glutathione disulfide
+
a hydroxy-fatty-acyl-[lipid]
+
H2O

Synonyms

AC-PHGPx, Bi-PHGPx, class 4 GPx, CsGPx1, CsGPx2, CsGPx3, CsGPx4, DMPHGPx, glutathione peroxidase 4, glutathione peroxidase-4, glutathione-dependent phospholipid peroxidase, GPX, GPx-4, GPX3, GPx4, GPx41, GPx4A, GPx4B, GPXhs2, GPXle1, hydroperoxide glutathione peroxidase, Hyr1, Hyr1/YIR037W, McPHGPx, More, non-selenocysteine PHGPx, NPGPx, nPHGPx, OsPHGPx, peroxidation-inhibiting protein, peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing), PHGPX, phospholipid glutathione peroxidase, phospholipid hydroperoxide glutathione peroxidase, phospholipid hydroperoxide glutathione peroxidase A, phospholipid hydroperoxide glutathione peroxidase B, phospholipid hydroperoxide glutathione peroxidase-4, phospholipid-hydroperoxide glutathione peroxidase, phospholipid-hydroperoxide glutathione peroxidases, selenium-dependent glutathione peroxidase type-4, seleno GPx, selenoperoxidase, selenoprotein P, sperm nucleus-specific glutathione peroxidase, type-4 glutathione peroxidase, VcPHGPx

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase

Substrates Products

Substrates Products on EC 1.11.1.12 - phospholipid-hydroperoxide glutathione peroxidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
glutathione + 1-palmitoyl-2-(13-hydroperoxy-cis-9,trans-11-octadecadienoyl)-3-phosphatidylcholine
?
show the reaction diagram
-
-
-
-
?
glutathione + 1-palmitoyl-2-(13-hydroperoxy-cis-9,trans-11-octadecadienoyl)-L-3-phosphatidylcholine
?
show the reaction diagram
-
-
-
-
?
glutathione + 3beta-hydroxycholest-5-ene-7alpha-hydroperoxide
cholest-5-ene-3beta,7alpha-diol + ?
show the reaction diagram
-
-
-
-
?
glutathione + a lipid hydroperoxide
glutathione disulfide + lipid + H2O
show the reaction diagram
glutathione + cardiolipin
?
show the reaction diagram
glutathione + cholesterol hydroperoxide
?
show the reaction diagram
-
-
-
-
?
glutathione + cholesterol hydroperoxides
?
show the reaction diagram
glutathione + cumene hydroperoxide
?
show the reaction diagram
glutathione + dilinoleoyl phosphatidylcholine hydroperoxide
?
show the reaction diagram
glutathione + fatty acid hydroperoxides
?
show the reaction diagram
-
-
-
-
?
glutathione + H2O2
?
show the reaction diagram
glutathione + L-alpha-phosphatidylcholine hydroperoxide
?
show the reaction diagram
glutathione + LDL hydroperoxides
?
show the reaction diagram
-
-
-
-
?
glutathione + linoleic acid hydroperoxide
?
show the reaction diagram
glutathione + lipid hydroperoxide
glutathione disulfide + lipid + H2O
show the reaction diagram
glutathione + phosphatidic acid hydroperoxide
?
show the reaction diagram
-
-
-
-
?
glutathione + phosphatidylcholine hydroperoxide
?
show the reaction diagram
glutathione + phosphatidylethanolamine hydroperoxide
?
show the reaction diagram
-
-
-
-
?
glutathione + phosphatidylserine hydroperoxide
?
show the reaction diagram
-
-
-
-
?
glutathione + phospholipid hydroperoxides
?
show the reaction diagram
glutathione + QKSPCCPKSP
?
show the reaction diagram
-
-
-
?
glutathione + t-butyl hydroperoxide
?
show the reaction diagram
-
-
-
-
?
glutathione + tert-butyl hydroperoxide
?
show the reaction diagram
glutathione + tert-butyl-hydroperoxide
?
show the reaction diagram
glutathione + tert-butylhydroperoxide
?
show the reaction diagram
-
-
-
-
?
GSH + cumene hydroperoxide
GSSG + ?
show the reaction diagram
GSH + H2O2
GSSG + ?
show the reaction diagram
-
about 50% of the activity with cumene hydroperoxide
-
-
?
GSH + linoleic acid hydroperoxide
GSSG + ?
show the reaction diagram
-
-
-
-
?
GSH + phosphatidylcholine dilinoleoyl hydroperoxide
GSSG + ?
show the reaction diagram
-
-
-
-
?
GSH + tert-butyl hydroperoxide
GSSG + ?
show the reaction diagram
KKSQCCQQKT + H2O2
KKSQ-L-cystinyl-QQKT + 2 H2O
show the reaction diagram
-
-
-
?
KPPCCPPK + H2O2
KPP-L-cystinyl-PPK + 2 H2O
show the reaction diagram
-
-
-
?
PKPPCCPPKP + H2O2
PKPP-L-cystinyl-PPKP + 2 H2O
show the reaction diagram
-
-
-
?
PKSPCCPPKP + H2O2
PKSP-L-cystinyl-PPKP + 2 H2O
show the reaction diagram
-
-
-
?
PKSPCCPPKS + H2O2
PKSP-L-cystinyl-PPKS + 2 H2O
show the reaction diagram
-
-
-
?
PPCCPP + H2O2
PP-L-cystinyl-PP + 2 H2O
show the reaction diagram
-
-
-
?
PPKPCCPPKP + H2O2
PPKP-L-cystinyl-PKP + 2 H2O
show the reaction diagram
-
-
-
?
PPPPCCPPPP + H2O2
PPPP-L-cystinyl-PPPP + 2 H2O
show the reaction diagram
-
-
-
?
QKPPCCPKSP + H2O2
QKPP-L-cystinyl-PKSP + 2 H2O
show the reaction diagram
-
-
-
?
thioredoxin + 1-palmitoyl-2-(13-hydroperoxy-cis-9,trans-11-octadecadienoyl)-L-3-phosphatidylcholine
?
show the reaction diagram
-
-
-
-
?
additional information
?
-