1.11.1.12: phospholipid-hydroperoxide glutathione peroxidase

This is an abbreviated version!
For detailed information about phospholipid-hydroperoxide glutathione peroxidase, go to the full flat file.

Word Map on EC 1.11.1.12

Reaction

2 glutathione +

a hydroperoxy-fatty-acyl-[lipid]
=
glutathione disulfide
+
a hydroxy-fatty-acyl-[lipid]
+
H2O

Synonyms

AC-PHGPx, Bi-PHGPx, class 4 GPx, CsGPx1, CsGPx2, CsGPx3, CsGPx4, DMPHGPx, glutathione peroxidase 4, glutathione peroxidase-4, glutathione-dependent phospholipid peroxidase, GPX, GPx-4, GPX3, GPx4, GPx41, GPx4A, GPx4B, GPXhs2, GPXle1, hydroperoxide glutathione peroxidase, Hyr1, Hyr1/YIR037W, McPHGPx, More, non-selenocysteine PHGPx, NPGPx, nPHGPx, OsPHGPx, peroxidation-inhibiting protein, peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing), PHGPX, phospholipid glutathione peroxidase, phospholipid hydroperoxide glutathione peroxidase, phospholipid hydroperoxide glutathione peroxidase A, phospholipid hydroperoxide glutathione peroxidase B, phospholipid hydroperoxide glutathione peroxidase-4, phospholipid-hydroperoxide glutathione peroxidase, phospholipid-hydroperoxide glutathione peroxidases, selenium-dependent glutathione peroxidase type-4, seleno GPx, selenoperoxidase, selenoprotein P, sperm nucleus-specific glutathione peroxidase, type-4 glutathione peroxidase, VcPHGPx

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase

Reference

Reference on EC 1.11.1.12 - phospholipid-hydroperoxide glutathione peroxidase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ursini, F.; Maiorini, M.; Gregolin, C.
The selenoenzyme phospholipid hydroperoxide glutathione peroxidase
Biochim. Biophys. Acta
839
62-70
1985
Sus scrofa
Manually annotated by BRENDA team
Maiorino, M.; Roveri, A.; Gregolin, C.; Ursini, F.
Different effects of Triton X-100, deoxycholate, and fatty acids on the kinetics of glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase
Arch. Biochem. Biophys.
251
600-605
1986
Sus scrofa
Manually annotated by BRENDA team
Panfili, E.; Sandri, G.; Ernster, L.
Distribution of glutathione peroxidases and glutathione reductase in rat brain mitochondria
FEBS Lett.
290
35-37
1991
Rattus norvegicus
Manually annotated by BRENDA team
Maiorino, M.; Gregolin, C.; Ursini, F.
Phospholipid hydroperoxide glutathione peroxidase
Methods Enzymol.
186
448-457
1990
Bos taurus, Canis lupus familiaris, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Ursini, F.; Maiorino, M.; Valente, M.; Ferri, L.; Gregolin, C.
Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides
Biochim. Biophys. Acta
710
197-211
1982
Sus scrofa
Manually annotated by BRENDA team
Maiorino, M.; Ursini, F.; Leonelli, M.; Finato, N.; Gregolin, C.
A pig heart peroxidation inhibiting protein with glutathione peroxidase activity on phospholipid hydroperoxides
Biochem. Int.
5
575-581
1982
Sus scrofa
-
Manually annotated by BRENDA team
Thomas, J.P.; Geiger, P.G.; Maiorino, M.; Ursini, F.; Girotti, A.W.
Enzymatic reduction of phospholipid and cholesterol hydroperoxides in artificial bilayers and lipoproteins
Biochim. Biophys. Acta
1045
252-260
1990
Sus scrofa
Manually annotated by BRENDA team
Zhang, L.; Maiorini, M.; Roveri, A.; Ursini, F.
Phospholipid hydroperoxide glutathione peroxidase: specific activity in tissues of rats of different age and comparison with other glutathione peroxidases
Biochim. Biophys. Acta
1006
140-143
1989
Rattus norvegicus
Manually annotated by BRENDA team
Avsian-Kretchmer, O.; Eshdat, Y.; Gueta-Dahan, Y.; Ben-Hayyim, G.
Regulation of stress-induced phospholipid hydroperoxide glutathione peroxidase expression in citrus
Planta
209
469-477
1999
Citrus sinensis
Manually annotated by BRENDA team
Saito, Y.; Hayashi, T.; Tanaka, A.; Watanabe, Y.; Suzuki, M.; Saito, E.; Takahashi, K.
Selenoprotein P in human plasma as an extracellular phospholipid hydroperoxide glutathione peroxidase. Isolation and enzymatic characterization of human selenoprotein P
J. Biol. Chem.
274
2866-2871
1999
Homo sapiens
Manually annotated by BRENDA team
Avery, A.M.; Avery, S.V.
Saccharomyces cerevisiae expresses three phospholipid hydroperoxide glutathione peroxidases
J. Biol. Chem.
276
33730-33735
2001
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Wilkinson, S.R.; Meyer, D.J.; Kelly, J.M.
Biochemical characterization of a trypanosome enzyme with glutathione-dependent peroxidase activity
Biochem. J.
352
755-761
2000
Trypanosoma cruzi
Manually annotated by BRENDA team
Lam, K.W.; Wang, L.; Hong, B.S.; Treble, D.
Purification of phospholipid hydroperoxide glutathione peroxidase from bovine retina
Curr. Eye Res.
12
9-15
1993
Bos taurus
Manually annotated by BRENDA team
Tramer, F.; Micali, F.; Sandri, G.; Bertoni, A.; Lenzi, A.; Gandini, L.; Panfili, E.
Enzymatic and immunochemical evaluation of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in testes and epididymal spermatozoa of rats of different ages
Int. J. Androl.
25
72-83
2002
Rattus norvegicus
Manually annotated by BRENDA team
Chambers, S.J.; Lambert, N.; Williamson, G.
Purification of a cytosolic enzyme from human liver with phospholipid hydroperoxide glutathione peroxidase activity
Int. J. Biochem.
26
1279-1286
1994
Homo sapiens
Manually annotated by BRENDA team
Schnurr, K.; Borchert, A.; Gerth, C.; Anton, M.; Kuhn, H.
Bacterial and nonbacterial expression of wild-type and mutant human phospholipid hydroperoxide glutathione peroxidase and purification of the mutant enzyme in the milligram scale
Protein Expr. Purif.
19
403-410
2000
Homo sapiens
Manually annotated by BRENDA team
Roveri, A.; Maiorino, M.; Nisii, C.; Ursini, F.
Purification and characterization of phospholipid hydroperoxide glutathione peroxidase from rat testis mitochondrial membranes
Biochim. Biophys. Acta
1208
211-221
1994
Rattus norvegicus
Manually annotated by BRENDA team
Sattler, W.; Maiorino, M.; Stocker, R.
Reduction of HDL- and LDL-associated cholesterylester and phospholipid hydroperoxides by phospholipid hydroperoxide glutathione peroxidase and ebselen (PZ 51)
Arch. Biochem. Biophys.
309
214-221
1994
Sus scrofa
Manually annotated by BRENDA team
Maiorino, M.; Roche, C.; Kiess, M.; Koenig, K.; Gawlik, D.; Matthes, M.; Naldini, E.; Pierce, R.; Flohe, L.
A selenium-containing phospholipid-hydroperoxide glutathione peroxidase in Schistosoma mansoni
Eur. J. Biochem.
238
838-844
1996
Schistosoma mansoni
Manually annotated by BRENDA team
Nomura, K.; Imai, H.; Koumura, T.; Kobayashi, T.; Nakagawa, Y.
Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis
Biochem. J.
351
183-193
2000
Rattus norvegicus
Manually annotated by BRENDA team
Foresta, C.; Flohe, L.; Garolla, A.; Roveri, A.; Ursini, F.; Maiorino, M.
Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase
Biol. Reprod.
67
967-971
2002
Homo sapiens
Manually annotated by BRENDA team
Nagdas, S.K.; Winfrey, V.P.; Olson, G.E.
Tyrosine phosphorylation generates multiple isoforms of the mitochondrial capsule protein, phospholipid hydroperoxide glutathione peroxidase (PHGPx), during hamster sperm capacitation
Biol. Reprod.
72
164-171
2005
Mesocricetus auratus
Manually annotated by BRENDA team
Herbette, S.; Lenne, C.; Leblanc, N.; Julien, J.L.; Drevet, J.R.; Roeckel-Drevet, P.
Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities
Eur. J. Biochem.
269
2414-2420
2002
Solanum lycopersicum
Manually annotated by BRENDA team
Maiorino, M.; Mauri, P.; Roveri, A.; Benazzi, L.; Toppo, S.; Bosello, V.; Ursini, F.
Primary structure of the nuclear forms of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in rat spermatozoa
FEBS Lett.
579
667-670
2005
Rattus norvegicus
Manually annotated by BRENDA team
Tramer, F.; Caponecchia, L.; Sgro, P.; Martinelli, M.; Sandri, G.; Panfili, E.; Lenzi, A.; Gandini, L.
Native specific activity of glutathione peroxidase (GPx-1), phospholipid hydroperoxide glutathione peroxidase (PHGPx) and glutathione reductase (GR)does not differ between normo- and hypomotile human sperm samples
Int. J. Androl.
27
88-93
2004
Homo sapiens
Manually annotated by BRENDA team
Utomo, A.; Jiang, X.; Furuta, S.; Yun, J.; Levin, D.S.; Wang, Y.C.; Desai, K.V.; Green, J.E.; Chen, P.L.; Lee, W.H.
Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells
J. Biol. Chem.
279
43522-43529
2004
Homo sapiens
Manually annotated by BRENDA team
Li, D.; Blasevich, F.; Theopold, U.; Schmidt, O.
Possible function of two insect phospholipid-hydroperoxide glutathione peroxidases
J. Insect Physiol.
49
1-9
2003
Drosophila melanogaster, Venturia canescens
Manually annotated by BRENDA team
Diaconu, M.; Tangat, Y.; Boehm, D.; Kuehn, H.; Michelmann, H.W.; Schreiber, G.; Haidl, G.; Glander, H.J.; Engel, W.; Nayernia, K.
Failure of phospholipid hydroperoxide glutathione peroxidase expression in oligoasthenozoospermia and mutations in the PHGPx gene
Andrologia
38
152-157
2006
Homo sapiens
Manually annotated by BRENDA team
Hattori, H.; Imai, H.; Furuhama, K.; Sato, O.; Nakagawa, Y.
Induction of phospholipid hydroperoxide glutathione peroxidase in human polymorphonuclear neutrophils and HL60 cells stimulated with TNF-alpha
Biochem. Biophys. Res. Commun.
337
464-473
2005
Homo sapiens
Manually annotated by BRENDA team
Hattori, H.; Imai, H.; Hanamoto, A.; Furuhama, K.; Nakagawa, Y.
Up-regulation of phospholipid hydroperoxide glutathione peroxidase in rat casein-induced polymorphonuclear neutrophils
Biochem. J.
389
279-287
2005
Rattus norvegicus
Manually annotated by BRENDA team
Januel, C.; El Hentati, F.; Carreras, M.; Arthur, J.R.; Calzada, C.; Lagarde, M.; Vericel, E.
Phospholipid-hydroperoxide glutathione peroxidase (GPx-4) localization in resting platelets, and compartmental change during platelet activation
Biochim. Biophys. Acta
1761
1228-1234
2006
Homo sapiens
Manually annotated by BRENDA team
Puglisi, R.; Tramer, F.; Carlomagno, G.; Gandini, L.; Panfili, E.; Stefanini, M.; Lenzi, A.; Mangia, F.; Boitani, C.
PHGPx in spermatogenesis: how many functions?
Contraception
72
291-293
2005
Rattus norvegicus
Manually annotated by BRENDA team
Lapointe, J.; Kimmins, S.; Maclaren, L.A.; Bilodeau, J.F.
Estrogen selectively up-regulates the phospholipid hydroperoxide glutathione peroxidase in the oviducts
Endocrinology
146
2583-2592
2005
Bos taurus, Bos taurus (Q9N2J2)
Manually annotated by BRENDA team
Steinbrenner, H.; Bilgic, E.; Alili, L.; Sies, H.; Brenneisen, P.
Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity
Free Radic. Res.
40
936-943
2006
Homo sapiens
Manually annotated by BRENDA team
Dash, B.; Metz, R.; Huebner, H.J.; Porter, W.; Phillips, T.D.
Molecular characterization of phospholipid hydroperoxide glutathione peroxidases from Hydra vulgaris
Gene
381
1-12
2006
Hydra vulgaris, Hydra vulgaris (Q072C7)
Manually annotated by BRENDA team
Schneider, M.; Vogt Weisenhorn, D.M.; Seiler, A.; Bornkamm, G.W.; Brielmeier, M.; Conrad, M.
Embryonic expression profile of phospholipid hydroperoxide glutathione peroxidase
Gene Expr. Patterns
6
489-494
2006
Mus musculus
Manually annotated by BRENDA team
Liu, J.; Du, J.; Zhang, Y.; Sun, W.; Smith, B.J.; Oberley, L.W.; Cullen, J.J.
Suppression of the malignant phenotype in pancreatic cancer by overexpression of phospholipid hydroperoxide glutathione peroxidase
Hum. Gene Ther.
17
105-116
2006
Homo sapiens
Manually annotated by BRENDA team
Cossio-Bayugar, R.; Miranda, E.; Holman, P.J.
Molecular cloning of a phospholipid-hydroperoxide glutathione peroxidase gene from the tick, Boophilus microplus (Acari: Ixodidae)
Insect Biochem. Mol. Biol.
35
1378-1387
2005
Rhipicephalus microplus (Q2XW19), Rhipicephalus microplus
Manually annotated by BRENDA team
Imai, H.; Saito, M.; Kirai, N.; Hasegawa, J.; Konishi, K.; Hattori, H.; Nishimura, M.; Naito, S.; Nakagawa, Y.
Identification of the positive regulatory and distinct core regions of promoters, and transcriptional regulation in three types of mouse phospholipid hydroperoxide glutathione peroxidase
J. Biochem.
140
573-590
2006
Mus musculus
Manually annotated by BRENDA team
Maiorino, M.; Roveri, A.; Benazzi, L.; Bosello, V.; Mauri, P.; Toppo, S.; Tosatto, S.C.; Ursini, F.
Functional interaction of phospholipid hydroperoxide glutathione peroxidase with sperm mitochondrion-associated cysteine-rich protein discloses the adjacent cysteine motif as a new substrate of the selenoperoxidase
J. Biol. Chem.
280
38395-38402
2005
Rattus norvegicus (P36970)
Manually annotated by BRENDA team
Borchert, A.; Wang, C.C.; Ufer, C.; Schiebel, H.; Savaskan, N.E.; Kuhn, H.
The role of phospholipid hydroperoxide glutathione peroxidase isoforms in murine embryogenesis
J. Biol. Chem.
281
19655-19664
2006
Mus musculus
Manually annotated by BRENDA team
Kriska, T.; Girotti, A.W.
A thin layer chromatographic method for determining the enzymatic activity of peroxidases catalyzing the two-electron reduction of lipid hydroperoxides
J. Chromatogr. B
827
58-64
2005
Homo sapiens
Manually annotated by BRENDA team
Conrad, M.; Moreno, S.G.; Sinowatz, F.; Ursini, F.; Koelle, S.; Roveri, A.; Brielmeier, M.; Wurst, W.; Maiorino, M.; Bornkamm, G.W.
The nuclear form of phospholipid hydroperoxide glutathione peroxidase is a protein thiol peroxidase contributing to sperm chromatin stability
Mol. Cell. Biol.
25
7637-7644
2005
Mus musculus
Manually annotated by BRENDA team
Yang, X.D.; Dong, C.J.; Liu, J.Y.
A plant mitochondrial phospholipid hydroperoxide glutathione peroxidase: its precise localization and higher enzymatic activity
Plant Mol. Biol.
62
951-962
2006
Raphanus sativus
Manually annotated by BRENDA team
Scheerer, P.; Borchert, A.; Krauss, N.; Wessner, H.; Gerth, C.; Hoehne, W.; Kuhn, H.
Structural basis for catalytic activity and enzyme polymerization of phospholipid hydroperoxide glutathione peroxidase-4 (GPx4)
Biochemistry
46
9041-9049
2007
Homo sapiens, Homo sapiens (P36969)
Manually annotated by BRENDA team
Conrad, M.; Schneider, M.; Seiler, A.; Bornkamm, G.W.
Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals
Biol. Chem.
388
1019-1025
2007
Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Wang, F.; Zhou, H.; Kong, B.; Fan, J.; Chen, H.; Liu, J.
Urea-induced inactivation and unfolding of recombinant phospholipid hydroperoxide glutathione peroxidase from Oryza sativa
Chem. Res. Chin. Univ.
23
562-566
2007
Oryza sativa
Manually annotated by BRENDA team
Puglisi, R.; Bevilacqua, A.; Carlomagno, G.; Lenzi, A.; Gandini, L.; Stefanini, M.; Mangia, F.; Boitani, C.
Mice overexpressing the mitochondrial phospholipid hydroperoxide glutathione peroxidase in male germ cells show abnormal spermatogenesis and reduced fertility
Endocrinology
148
4302-4309
2007
Mus musculus, Mus musculus (O70325)
Manually annotated by BRENDA team
Dabkowski, E.R.; Williamson, C.L.; Hollander, J.M.
Mitochondria-specific transgenic overexpression of phospholipid hydroperoxide glutathione peroxidase (GPx4) attenuates ischemia/reperfusion-associated cardiac dysfunction
Free Radic. Biol. Med.
45
855-865
2008
Mus musculus, Mus musculus (O70325)
Manually annotated by BRENDA team
Cejas, P.; Garcia-Cabezas, M.A.; Casado, E.; Belda-Iniesta, C.; De Castro, J.; Fresno, J.A.; Sereno, M.; Barriuso, J.; Espinosa, E.; Zamora, P.; Feliu, J.; Redondo, A.; Hardisson, D.A.; Renart, J.; Gonzalez-Baron, M.
Phospholipid hydroperoxide glutathione peroxidase (PHGPx) expression is downregulated in poorly differentiated breast invasive ductal carcinoma
Free Radic. Res.
41
681-687
2007
Homo sapiens
Manually annotated by BRENDA team
Cai, G.B.; Bae, Y.A.; Kim, S.H.; Sohn, W.M.; Lee, Y.S.; Jiang, M.S.; Kim, T.S.; Kong, Y.
Vitellocyte-specific expression of phospholipid hydroperoxide glutathione peroxidases in Clonorchis sinensis
Int. J. Parasitol.
38
1613-1623
2008
Clonorchis sinensis (A0SWV9), Clonorchis sinensis (A0SWW0), Clonorchis sinensis (A0SWW1), Clonorchis sinensis (A0SWW2), Clonorchis sinensis
Manually annotated by BRENDA team
Wang, Z.; Wang, F.; Duan, R.; Liu, J.Y.
Purification and physicochemical characterization of a recombinant phospholipid hydroperoxide glutathione peroxidase from Oryza sativa
J. Biochem. Mol. Biol.
40
412-418
2007
Oryza sativa
Manually annotated by BRENDA team
Baek, I.J.; Seo, D.S.; Yon, J.M.; Lee, S.R.; Jin, Y.; Nahm, S.S.; Jeong, J.H.; Choo, Y.K.; Kang, J.K.; Lee, B.J.; Yun, Y.W.; Nam, S.Y.
Tissue expression and cellular localization of phospholipid hydroperoxide glutathione peroxidase (PHGPx) mRNA in male mice
J. Mol. Histol.
38
237-244
2007
Mus musculus
Manually annotated by BRENDA team
Baek, I.J.; Yon, J.M.; Lee, S.R.; Jin, Y.; Kim, M.R.; Ahn, B.; Hong, J.T.; Choo, Y.K.; Lee, B.J.; Yun, Y.W.; Nam, S.Y.
Effects of endocrine disrupting chemicals on expression of phospholipid hydroperoxide glutathione peroxidase mRNA in rat testes
J. Vet. Sci.
8
213-218
2007
Rattus norvegicus
Manually annotated by BRENDA team
Ding, W.Q.; Lind, S.E.
Phospholipid hydroperoxide glutathione peroxidase plays a role in protecting cancer cells from docosahexaenoic acid-induced cytotoxicity
Mol. Cancer Ther.
6
1467-1474
2007
Homo sapiens
Manually annotated by BRENDA team
Zafiriou, M.P.; Deva, R.; Ciccoli, R.; Siafaka-Kapadai, A.; Nigam, S.
Biological role of hepoxilins: upregulation of phospholipid hydroperoxide glutathione peroxidase as a cellular response to oxidative stress?
Prostaglandins Leukot. Essent. Fatty Acids
77
209-215
2007
Rattus norvegicus
Manually annotated by BRENDA team
Dong, C.J.; Yang, X.D.; Liu, J.Y.
Enzymatic properties of a recombinant phospholipid hydroperoxide glutathione peroxidase from Momordica charantia and its complementation function in yeast
Biochemistry (Moscow)
74
502-508
2009
Momordica charantia, Momordica charantia (Q8W259)
Manually annotated by BRENDA team
Conrad, M.
Transgenic mouse models for the vital selenoenzymes cytosolic thioredoxin reductase, mitochondrial thioredoxin reductase and glutathione peroxidase 4
Biochim. Biophys. Acta
1790
1575-1585
2009
Mus musculus
Manually annotated by BRENDA team
Bae, Y.; Cai, G.; Kim, S.; Zo, Y.; Kong, Y.
Modular evolution of glutathione peroxidase genes in association with different biochemical properties of their encoded proteins in invertebrate animals
BMC Evol. Biol.
9
72
2009
animal
Manually annotated by BRENDA team
Hu, Z.; Lee, K.S.; Choo, Y.M.; Yoon, H.J.; Kim, I.; Wei, Y.D.; Gui, Z.Z.; Zhang, G.Z.; Sohn, H.D.; Jin, B.R.
Molecular characterization of a phospholipid-hydroperoxide glutathione peroxidase from the bumblebee Bombus ignitus
Comp. Biochem. Physiol. B
155
54-61
2010
Bombus ignitus, Bombus ignitus (C3VVL8)
Manually annotated by BRENDA team
Hermesz, E.; Ferencz, A.
Identification of two phospholipid hydroperoxide glutathione peroxidase (gpx4) genes in common carp
Comp. Biochem. Physiol. C
150
101-106
2009
Cyprinus carpio
Manually annotated by BRENDA team
Kadota, Y.; Suzuki, S.; Ideta, S.; Fukinbara, Y.; Kawakami, T.; Imai, H.; Nakagawa, Y.; Sato, M.
Enhanced metallothionein gene expression induced by mitochondrial oxidative stress is reduced in phospholipid hydroperoxide glutathione peroxidase-overexpressed cells
Eur. J. Pharmacol.
626
166-170
2009
Rattus norvegicus
Manually annotated by BRENDA team
Chen, H.; Lin, C.; Ken, C.; Wen, L.; Lin, C.
Putative phospholipid hydroperoxide glutathione peroxidase from Antrodia camphorata
Food Chem.
115
476-482
2009
Taiwanofungus camphoratus (B8K1J5)
Manually annotated by BRENDA team
Guo, Z.; Ran, Q.; Roberts, L.J.; Zhou, L.; Richardson, A.; Sharan, C.; Wu, D.; Yang, H.
Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice
Free Radic. Biol. Med.
44
343-352
2008
Homo sapiens
Manually annotated by BRENDA team
Li, T.; Yang, X.; Liu, J.
Tissue and induction expression profiles of rice phospholipid hydroperoxide glutathione peroxidase at protein level
Prog. Biochem. Biophys.
36
77-82
2009
Oryza sativa
-
Manually annotated by BRENDA team
Kernstock, R.M.; Girotti, A.W.
New strategies for the isolation and activity determination of naturally occurring type-4 glutathione peroxidase
Protein Expr. Purif.
62
216-222
2008
Rattus norvegicus
Manually annotated by BRENDA team
Zhang, W.; He, Y.; Yang, Z.; Yu, J.; Chen, Y.; Zhou, C.
Crystal structure of glutathione-dependent phospholipid peroxidase Hyr1 from the yeast Saccharomyces cerevisiae
Proteins Struct. Funct. Genet.
73
1058-1062
2008
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Dimastrogiovanni, D.; Anselmi, M.; Miele, A.E.; Boumis, G.; Petersson, L.; Angelucci, F.; Nola, A.D.; Brunori, M.; Bellelli, A.
Combining crystallography and molecular dynamics: The case of Schistosoma mansoni phospholipid glutathione peroxidase
Proteins
78
259-270
2009
Schistosoma mansoni
Manually annotated by BRENDA team
Stradaioli, G.; Sylla, L.; Monaci, M.; Maiorino, M.
Phospholipid hydroperoxide glutathione peroxidase in bull spermatozoa provides a unique marker in the quest for semen quality analysis
Theriogenology
72
91-98
2009
Bos taurus
Manually annotated by BRENDA team
Baseler, W.A.; Dabkowski, E.R.; Jagannathan, R.; Thapa, D.; Nichols, C.E.; Shepherd, D.L.; Croston, T.L.; Powell, M.; Razunguzwa, T.T.; Lewis, S.E.; Schnell, D.M.; Hollander, J.M.
Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase
Am. J. Physiol. Regul. Integr. Comp. Physiol.
304
R553-R565
2013
Mus musculus
Manually annotated by BRENDA team
Han, X.; Fan, Z.; Yu, Y.; Liu, S.; Hao, Y.; Huo, R.; Wei, J.
Expression and characterization of recombinant human phospholipid hydroperoxide glutathione peroxidase
IUBMB Life
65
951-956
2013
Homo sapiens (D6W5Y2), Homo sapiens
Manually annotated by BRENDA team
Janowski, R.; Scanu, S.; Niessing, D.; Madl, T.
Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4
Acta Crystallogr. Sect. F
72
743-749
2016
Mus musculus, Mus musculus (O70325)
Manually annotated by BRENDA team
Yu, Y.; Song, J.; Guo, X.; Wang, S.; Yang, X.; Chen, L.; Wei, J.
Characterization and structural analysis of human selenium-dependent glutathione peroxidase 4 mutant expressed in Escherichia coli
Free Radic. Biol. Med.
71
332-338
2014
Homo sapiens, Homo sapiens (P36969)
Manually annotated by BRENDA team