1.10.5.1: ribosyldihydronicotinamide dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about ribosyldihydronicotinamide dehydrogenase (quinone), go to the full flat file.

Word Map on EC 1.10.5.1

Reaction

1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide
+
a quinone
=
1-(beta-D-ribofuranosyl)nicotinamide
+
a quinol

Synonyms

bQR2, dihydronicotinamide riboside:quinone oxidoreductase, dihydronicotinamide riboside:quinone oxidoreductase 2, dihydronicotinamide riboside:quinone reductase 2, EC 1.10.99.2, melatonin-binding site MT3, MT3, MT3/NQO2, N-ribosyldihydronicotinamide dehydrogenase (quinone), N-ribosyldihydronicotinamide:quinone oxidoreductase 2, NQO2, NRH-oxidizing enzyme, NRH:QR2, NRH:quinone oxidoreductase, NRH:quinone oxidoreductase 2, NRH:quinone oxireductase 2, NRH:quinone reductase 2, QR2, quinone oxidoreductase 2, quinone reductase 2, quinone reductase type 2

ECTree

     1 Oxidoreductases
         1.10 Acting on diphenols and related substances as donors
             1.10.5 With a quinone or related compound as acceptor
                1.10.5.1 ribosyldihydronicotinamide dehydrogenase (quinone)

KM Value

KM Value on EC 1.10.5.1 - ribosyldihydronicotinamide dehydrogenase (quinone)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00075
17beta-17-hydroxyestr-1(10)-ene-3,4-dione
-
-
0.007 - 0.019
2,6-dichlorophenolindophenol
0.012
3-(4,5-dimethylthiazaol-2-yl)-2,5-diphenyltetrazolium
-
-
0.061
5-(aziridin-1-yl)-2,4-dinitrobenzamide
-
at 25°C in pH 8.5 buffer (50 mM Tris, 140 mM NaCl, and 0.1% Tween 20) with 0.1 mM menadione as co-substrate
0.26
CB 1954
-
-
0.0137
coenzyme Q0
-
using N-benzyl dihydronicotinamide as cosubstrate, at 25°C, in 50 mM Tris-HCl, pH 8.5
0.0517
coenzyme Q1
-
using N-benzyl dihydronicotinamide as cosubstrate, at 25°C, in 50 mM Tris-HCl, pH 8.5
0.0387
coenzyme Q2
-
using N-benzyl dihydronicotinamide as cosubstrate, at 25°C, in 50 mM Tris-HCl, pH 8.5
0.02 - 0.0608
dihydrobenzylnicotinamide
0.028
dihydronicotinamide riboside
-
-
0.000033
estradiol-3,4-quinone
-
-
0.0016 - 0.0252
menadione
0.0023
menadione/3-(4,5-dimethylthiazaol-2-yl)-2,5-diphenyltetrazolium
-
-
0.0047
Methyl red
-
-
0.0113 - 0.0602
N-benzyl dihydronicotinamide
0.02
N-benzyldihydronicotinamide
-
-
0.252
NADH
-
-
0.023
reduced N1-(n-propyl)-nicotinamide
-
pH 7.6
2
tetrahydrofolate
-
-
additional information
additional information
-
steady-state kinetic, overview
-