1.10.5.1: ribosyldihydronicotinamide dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about ribosyldihydronicotinamide dehydrogenase (quinone), go to the full flat file.

Word Map on EC 1.10.5.1

Reaction

1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide
+
a quinone
=
1-(beta-D-ribofuranosyl)nicotinamide
+
a quinol

Synonyms

bQR2, dihydronicotinamide riboside:quinone oxidoreductase, dihydronicotinamide riboside:quinone oxidoreductase 2, dihydronicotinamide riboside:quinone reductase 2, EC 1.10.99.2, melatonin-binding site MT3, MT3, MT3/NQO2, N-ribosyldihydronicotinamide dehydrogenase (quinone), N-ribosyldihydronicotinamide:quinone oxidoreductase 2, NQO2, NRH-oxidizing enzyme, NRH:QR2, NRH:quinone oxidoreductase, NRH:quinone oxidoreductase 2, NRH:quinone oxireductase 2, NRH:quinone reductase 2, QR2, quinone oxidoreductase 2, quinone reductase 2, quinone reductase type 2

ECTree

     1 Oxidoreductases
         1.10 Acting on diphenols and related substances as donors
             1.10.5 With a quinone or related compound as acceptor
                1.10.5.1 ribosyldihydronicotinamide dehydrogenase (quinone)

KI Value

KI Value on EC 1.10.5.1 - ribosyldihydronicotinamide dehydrogenase (quinone)

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.012 - 0.033
2-iodo-5-methoxycarbonylamino-N-acetyltryptamine
0.004 - 0.05
2-iodo-melatonin
0.0012 - 0.029
2-iodomelatonin
0.0435 - 0.376
5-methoxycarbonylamino-N-acetyltryptamine
0.00061
Chloroquine
-
-
0.07
dabigatran
-
pH and temperature not specified in the publication
0.0009
dabigatran ethyl ester
-
pH and temperature not specified in the publication
0.566 - 0.62
dicoumarol
0.017
mefloquine
-
-
0.0072 - 0.246
Melatonin
0.092 - 0.204
N-acetylserotonin
0.00008 - 0.00031
N-[2-(2-iodo-5-methoxy-1-methyl-4-nitroindol-3-yl)ethyl]acetamide
0.00003 - 0.00004
N-[2-(2-methoxy-6H-dipyrido[2,3-a:3,2-e]pyrrolizin-11-yl)ethyl]-2-furamide
0.00104
primaquine
-
-
0.000021
quercetin
-
-
0.00051
Quinacrine
-
-
0.252
Quinine
-
-
0.00005 - 0.000088
resveratrol
0.0028 - 0.0414
S26553
0.00018 - 0.0009
S28128
2.933
serotonin
-
-
additional information
additional information
-
Michaelis-Menten inhibition kinetics
-