1.10.3.5: 3-hydroxyanthranilate oxidase

This is an abbreviated version!
For detailed information about 3-hydroxyanthranilate oxidase, go to the full flat file.

Word Map on EC 1.10.3.5

Reaction

3-Hydroxyanthranilate
+
O2
=
6-imino-5-oxocyclohexa-1,3-dienecarboxylate
+
H2O2

Synonyms

3-hydroxyanthranilic acid dioxygenase, 3-hydroxyanthranilic acid oxidase, 3HAO, o-aminophenol:O2 oxidoreductase, phenoxazine-synthetase

ECTree

     1 Oxidoreductases
         1.10 Acting on diphenols and related substances as donors
             1.10.3 With oxygen as acceptor
                1.10.3.5 3-hydroxyanthranilate oxidase

Disease

Disease on EC 1.10.3.5 - 3-hydroxyanthranilate oxidase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Leukemia
[Tryptophan conversion to nicotinic acid in mice with Friend's leukemia. I. 3-Hydroxyanthranilic acid oxidase activity.]
Pellagra
Tryptophan metabolism in alcoholic pellagra patients: measurements of urinary metabolites and histochemical studies of related muscle enzymes.
Seizures
Differential expression of the astrocytic enzymes 3-hydroxyanthranilic acid oxygenase, kynurenine aminotransferase and glutamine synthetase in seizure-prone and non-epileptic mice.
Effects of oxygen on 3-hydroxyanthranilate oxidase of the kynurenine pathway.