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1.1.99.40: (R)-2-hydroxyglutarate-pyruvate transhydrogenase

This is an abbreviated version!
For detailed information about (R)-2-hydroxyglutarate-pyruvate transhydrogenase, go to the full flat file.

Reaction

(R)-2-hydroxyglutarate
+
pyruvate
=
2-oxoglutarate
+
(R)-lactate

Synonyms

D-2-hydroxyglutarate-pyruvate transhydrogenase, DLD3

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.40 (R)-2-hydroxyglutarate-pyruvate transhydrogenase

Substrates Products

Substrates Products on EC 1.1.99.40 - (R)-2-hydroxyglutarate-pyruvate transhydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-oxoglutarate + D-lactate
D-2-hydroxyglutarate + pyruvate
show the reaction diagram
-
-
-
r
D-2-hydroxyglutarate + oxaloacetate
2-oxoglutarate + malate
show the reaction diagram
-
-
-
r
D-2-hydroxyglutarate + pyruvate
2-oxoglutarate + D-lactate
show the reaction diagram
-
-
-
r
additional information
?
-
no substrate: L-lactate. The enzyme displays dehydrogenase activity with artificial acceptor dichlorophenolindophenol
-
-
?