1.1.99.40: (R)-2-hydroxyglutarate-pyruvate transhydrogenase

This is an abbreviated version!
For detailed information about (R)-2-hydroxyglutarate-pyruvate transhydrogenase, go to the full flat file.

Reaction

(R)-2-hydroxyglutarate
+
pyruvate
=
2-oxoglutarate
+
(R)-lactate

Synonyms

D-2-hydroxyglutarate-pyruvate transhydrogenase, DLD3

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.40 (R)-2-hydroxyglutarate-pyruvate transhydrogenase

Reference

Reference on EC 1.1.99.40 - (R)-2-hydroxyglutarate-pyruvate transhydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Becker-Kettern, J.; Paczia, N.; Conrotte, J.F.; Kay, D.P.; Guignard, C.; Jung, P.P.; Linster, C.L.
Saccharomyces cerevisiae forms D-2-hydroxyglutarate and couples its degradation to D-lactate formation via a cytosolic transhydrogenase
J. Biol. Chem.
291
6036-6058
2016
Saccharomyces cerevisiae (P39976)
Manually annotated by BRENDA team