1.1.99.39: D-2-hydroxyglutarate dehydrogenase

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For detailed information about D-2-hydroxyglutarate dehydrogenase, go to the full flat file.

Reaction

Synonyms

2-hydroxyglutarate dehydrogenase, AtD-2HGDH, D-2-HG dehydrogenase, D-2-HGA, D-2-hydroxyglutarate dehydrogenase, D2-hydroxyglutarate dehydrogenase, D2HDH, D2HGDH

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.99 With unknown physiological acceptors

                1.1.99.39 D-2-hydroxyglutarate dehydrogenase

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Results	in table
21	AA Sequence
5	Cloned(Commentary)
5	Cofactor
57	Disease/ Diagnostics
1	Expression
11	General Information
6	kcat/KM [mM/s]
7	KM Value [mM]
3	Localization
1	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
17	Organism
1	Pathway
2	pH Optimum
7	Protein Variants
4	Purification (Commentary)
1	Reaction
11	Reference
7	Source Tissue
21	Substrates and Products (Substrate)
2	Subunits
15	Synonyms
1	Systematic Name
7	Turnover Number [1/s]

Expression

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Expression on EC 1.1.99.39 - D-2-hydroxyglutarate dehydrogenase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

expression of the enzyme is upregulated in the presence of high endogenous concentrations of (S)-2-hydroxyglutarate

Homo sapiens

Q8N465

763736