1.1.99.38: 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)

This is an abbreviated version!
For detailed information about 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent), go to the full flat file.

Reaction

2-deoxy-scyllo-inosamine
+
S-adenosyl-L-methionine
=
3-amino-2,3-dideoxy-scyllo-inosose
+
5'-deoxyadenosine
+
L-methionine

Synonyms

BtrN, DOIA dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.38 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)

Reference

Reference on EC 1.1.99.38 - 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yokoyama, K.; Ohmori, D.; Kudo, F.; Eguchi, T.
Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy
Biochemistry
47
8950-8960
2008
Bacillus circulans (Q8G907)
Manually annotated by BRENDA team
Yokoyama, K.; Numakura, M.; Kudo, F.; Ohmori, D.; Eguchi, T.
Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin
J. Am. Chem. Soc.
129
15147-15155
2007
Bacillus circulans (Q8G907)
Manually annotated by BRENDA team
Grove, T.L.; Ahlum, J.H.; Sharma, P.; Krebs, C.; Booker, S.J.
A consensus mechanism for radical SAM-dependent dehydrogenation? BtrN contains two [4Fe-4S] clusters
Biochemistry
49
3783-3785
2010
Bacillus circulans (Q8G907)
Manually annotated by BRENDA team
Maiocco, S.J.; Grove, T.L.; Booker, S.J.; Elliott, S.J.
Electrochemical resolution of the [4Fe-4S] centers of the AdoMet radical enzyme BtrN: evidence of proton coupling and an unusual, low-potential auxiliary cluster
J. Am. Chem. Soc.
137
8664-8667
2015
Bacillus circulans (Q8G907)
Manually annotated by BRENDA team
Goldman, P.J.; Grove, T.L.; Booker, S.J.; Drennan, C.L.
X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry
Proc. Natl. Acad. Sci. USA
110
15949-15954
2013
Bacillus circulans, Bacillus circulans (Q8G907)
Manually annotated by BRENDA team