1.1.99.31: (S)-mandelate dehydrogenase

This is an abbreviated version!
For detailed information about (S)-mandelate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.99.31

Reaction

(S)-Mandelate
+
acceptor
=
phenylglyoxylate
+
reduced acceptor

Synonyms

(S)-mandelate dehydrogenase, L-mandelate dehydrogenase, L-MDH, MDH, SManDH, SMDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.31 (S)-mandelate dehydrogenase

Substrates Products

Substrates Products on EC 1.1.99.31 - (S)-mandelate dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(R,S)-2-hydroxy-3-butenoic acid + acceptor
2-oxo-3-butenoic acid + reduced acceptor
show the reaction diagram
(R,S)-2-hydroxybutyrate + acceptor
2-oxobutyrate + reduced acceptor
show the reaction diagram
slow substrate
-
-
?
(R,S)-2-hydroxybutyric acid + acceptor
2-oxo-3-butynoic acid + reduced acceptor
show the reaction diagram
very low binding affinity for MDH
-
-
?
(R,S)-2-hydroxyhexanoate + acceptor
2-oxohexanoate + reduced acceptor
show the reaction diagram
-
-
-
?
(R,S)-2-hydroxyisocaproate + acceptor
2-oxoisocaproate + reduced acceptor
show the reaction diagram
-
-
-
?
(R,S)-2-hydroxyisovalerate + acceptor
2-oxo-isovalerate + reduced acceptor
show the reaction diagram
(R,S)-2-hydroxyoctanoate + acceptor
2-oxooctanoate + reduced acceptor
show the reaction diagram
slow substrate
-
-
?
(R,S)-2-hydroxyvalerate + acceptor
2-oxovalerate + reduced acceptor
show the reaction diagram
-
-
-
?
(R,S)-3-indolelactate + acceptor
3-(1H-indol-2-yl)-2-oxopropanoate + reduced acceptor
show the reaction diagram
-
-
-
?
(R,S)-3-phenyllactate + 2,6-dichlorophenolindophenol
phenylpyruvate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
slow substrate
-
-
?
(R,S)-indoleglycolate + acceptor
indol-2-yl(oxo)acetate + reduced acceptor
show the reaction diagram
-
-
-
?
(R,S)-mandelate + 2,6-dichlorophenolindophenol
2-oxo-2-phenylacetate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
-
-
?
(R,S)-mandelate + ferricyanide
2-oxo-2-phenylacetate + ferrocyanide
show the reaction diagram
-
-
-
?
(R,S)-p-chloromandelate + acceptor
?
show the reaction diagram
-
-
-
-
?
(S)-2-hydroxy-2-phenylacetate + O2
2-oxo-2-phenylacetate + H2O2
show the reaction diagram
-
in absence of any other electron acceptor, oxygen is used by the wild-type enzyme for reoxidation of the reduced flavin, at a rather slow rate. Ping-pong kinetics
-
-
?
(S)-3-phenyllactate + acceptor
?
show the reaction diagram
-
-
-
-
?
(S)-mandelate + 2 ferricyanide
2-oxo-2-phenylacetate + 2 ferrocyanide + 2 H+
show the reaction diagram
(S)-mandelate + 2 ferricyanide
benzoylformic acid + 2 ferrocyanide + 2 H+
show the reaction diagram
-
-
-
-
?
(S)-mandelate + 2,6-dichloroindophenol
2-oxo-2-phenylacetate + ?
show the reaction diagram
-
-
-
-
?
(S)-mandelate + 2,6-dichlorophenolindophenol
2-oxo-2-phenylacetate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
-
-
-
?
(S)-mandelate + acceptor
2-oxo-2-phenylacetate + reduced acceptor
show the reaction diagram
(S)-mandelate + acceptor
benzoylformate + reduced acceptor
show the reaction diagram
-
-
-
-
?
(S)-mandelate + cytochrome c
2-oxo-2-phenylacetate + ?
show the reaction diagram
-
-
-
-
?
(S)-mandelate + FMN
benzoylformic acid + FMNH2
show the reaction diagram
-
-
-
-
?
(S)-mandelate + FMN
phenylglyoxylate + FMNH2
show the reaction diagram
(S)-phenyllactate + 2,6-dichlorophenolindophenol
?
show the reaction diagram
-
-
-
-
?
2-hydroxy-3-butynoate + acceptor
2-oxo-3-butynoate + reduced acceptor
show the reaction diagram
2-hydroxybutyrate + acceptor
2-oxobutyrate + reduced acceptor
show the reaction diagram
-
-
-
-
?
2-hydroxyhexanoate + acceptor
2-oxohexanoate + reduced acceptor
show the reaction diagram
-
-
-
-
?
2-hydroxyisocaproate + acceptor
2-oxoisocaproate + reduced acceptor
show the reaction diagram
-
-
-
-
?
2-hydroxyoctanoate + acceptor
2-oxooctanoate + reduced acceptor
show the reaction diagram
-
-
-
-
?
2-hydroxyoctanoate + acceptor
? + reduced acceptor
show the reaction diagram
-
-
-
-
?
2-hydroxyvalerate + acceptor
2-oxovalerate + reduced acceptor
show the reaction diagram
-
-
-
-
?
3-hydroxy-DL-mandelate + ferricyanide
2-oxo-2-(3-hydroxyphenyl)acetate + ferrocyanide + H2O
show the reaction diagram
-
-
-
-
?
3-indolelactate + acceptor
3-(1H-indol-2-yl)-2-oxopropanoate + reduced acceptor
show the reaction diagram
-
-
-
-
?
3-indolelactate + acceptor
? + reduced acceptor
show the reaction diagram
-
-
-
-
?
3-methoxy-DL-mandelate + ferricyanide
2-oxo-2-(3-methoxyphenyl)acetate + ferrocyanide + H2O
show the reaction diagram
-
-
-
-
?
3-phenyllactate + acceptor
2-oxo-3-phenylpropanoate + reduced acceptor
show the reaction diagram
-
-
-
-
?
4-bromo-DL-mandelate + ferricyanide
2-oxo-2-(4-bromophenyl)acetate + ferrocyanide + H2O
show the reaction diagram
-
-
-
-
?
4-chloro-DL-mandelate + ferricyanide
2-oxo-2-(4-chlorophenyl)acetate + ferrocyanide + H2O
show the reaction diagram
-
-
-
-
?
4-chloromandelate + acceptor
2-oxo-2-(4-chlorophenyl)acetate + reduced acceptor
show the reaction diagram
-
-
-
-
?
4-fluoro-D,L-mandelate + ferricyanide
2-oxo-2-(4-fluorophenyl)acetate + ferrocyanide + H2O
show the reaction diagram
-
-
-
-
?
4-hydroxy-DL-mandelate + ferricyanide
2-oxo-2-(4-hydroxyphenyl)acetate + ferrocyanide + H2O
show the reaction diagram
-
-
-
-
?
4-methoxy-DL-mandelate + ferricyanide
2-oxo-2-(4-methoxyphenyl)acetate + ferrocyanide + H2O
show the reaction diagram
-
-
-
-
?
4-methyl-DL-mandelate + ferricyanide
2-oxo-2-(4-methylphenyl)acetate + ferrocyanide + H2O
show the reaction diagram
-
-
-
-
?
DL-mandelate + ferricyanide
2-oxo-2-phenylacetate + ferrocyanide + H2O
show the reaction diagram
ethyl-(S)-mandelate + acceptor
?
show the reaction diagram
-
-
-
-
?
indoleglycolate + acceptor
indol-2-yl(oxo)acetate + reduced acceptor
show the reaction diagram
-
-
-
-
?
L-mandelate + ferricyanide
2-oxo-2-phenylacetate + ferrocyanide
show the reaction diagram
-
-
-
-
?
mandelate + acceptor
2-oxo-2-phenylacetate + reduced acceptor
show the reaction diagram
methyl-(S)-mandelate + acceptor
?
show the reaction diagram
-
-
-
-
?
additional information
?
-