1.1.99.31: (S)-mandelate dehydrogenase

This is an abbreviated version!
For detailed information about (S)-mandelate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.99.31

Reaction

(S)-Mandelate
+
acceptor
=
phenylglyoxylate
+
reduced acceptor

Synonyms

(S)-mandelate dehydrogenase, L-mandelate dehydrogenase, L-MDH, MDH, SManDH, SMDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.31 (S)-mandelate dehydrogenase

Inhibitors

Inhibitors on EC 1.1.99.31 - (S)-mandelate dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(R)-mandelate
-
-
(R,S)-2-hydroxy-3-butynoic acid
irreversible inactivation
(S)-1-phenyl-1,2-ethanediol
(S)-1-phenyl-2,2,2-trifluoroethanol
competitive inhibitor
(S)-1-phenyl-2-propen-1-ol
-
(S)-1-phenyl-2-propyn-1-ol
-
(S)-2-methoxy-2-phenylacetate
competitive inhibitor
(S)-3-phenyllactate
competitive inhibitor
2-phenylacetate
competitive inhibitor
2-phenylethanoate
-
-
L-Phenyllactate
-
-
p-chloromercuribenzoate
-
10-20% inhibition at 0.01 mM
phenylethanediol
-
poor competitive inhibitor of wild-type enzyme