1.1.99.27: (R)-pantolactone dehydrogenase (flavin)

This is an abbreviated version!
For detailed information about (R)-pantolactone dehydrogenase (flavin), go to the full flat file.

Reaction

(R)-pantolactone
+
acceptor
=
2-dehydropantolactone
+
reduced acceptor

Synonyms

(R)-Pantoyllactone dehydrogenase (flavin), 2-Dehydropantolactone reductase (flavin), 2-Dehydropantoyl-lactone reductase (flavin), dehydrogenase, L-(+)-pantoyllactone

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.27 (R)-pantolactone dehydrogenase (flavin)

Systematic Name

Systematic Name on EC 1.1.99.27 - (R)-pantolactone dehydrogenase (flavin)

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SYSTEMATIC NAME
IUBMB Comments
(R)-pantolactone:acceptor oxidoreductase (flavin-containing)
High specificity for (R)-pantolactone. Phenazine methosulfate (PMS) can act as acceptor. The enzyme has been studied in the bacterium Nocardia asteroides and shown to be membrane-bound and induced by 1,2-propanediol. The FMN cofactor is non-covalently bound.