1.1.99.27: (R)-pantolactone dehydrogenase (flavin)

This is an abbreviated version!
For detailed information about (R)-pantolactone dehydrogenase (flavin), go to the full flat file.

Reaction

(R)-pantolactone
+
acceptor
=
2-dehydropantolactone
+
reduced acceptor

Synonyms

(R)-Pantoyllactone dehydrogenase (flavin), 2-Dehydropantolactone reductase (flavin), 2-Dehydropantoyl-lactone reductase (flavin), dehydrogenase, L-(+)-pantoyllactone

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.27 (R)-pantolactone dehydrogenase (flavin)

Inhibitors

Inhibitors on EC 1.1.99.27 - (R)-pantolactone dehydrogenase (flavin)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(R)-pantolactone
-
-
2-Dehydropantonolactone
-
20 mM
5,5'-dithiobis(2-nitrobenzoate)
-
1 mM, 47% inhibition
Atebrin
-
1 mM, 32.6% inhibition
Barbital
-
1 mM, 54.5% inhibition
CoCl2
-
1 mM, 24.4% inhibition
Diphenylhydantoin
-
1 mM, 22.1% inhibition
iodoacetate
-
1 mM, 17.4% inhibition
MnCl2
-
1 mM, 86.2% inhibition
NaAsO2
-
1 mM, 41% inhibition
NaCN
-
1 mM, 51.9% inhibition
NaF
-
1 mM, 27.3% inhibition
NaN3
-
1 mM, 9.1% inhibition
NEM
-
1 mM, 33.8% inhibition
NH2OH*HCl
-
1 mM, 71.9% inhibition
PCMB
-
1 mM, 41.0% inhibition
riboflavin
-
1 mM, 74.9% inhibition
Semicarbazide
-
1 mM, 23.1% inhibition