1.1.99.21: D-sorbitol dehydrogenase (acceptor)

This is an abbreviated version!
For detailed information about D-sorbitol dehydrogenase (acceptor), go to the full flat file.

Word Map on EC 1.1.99.21

Reaction

D-sorbitol
+
acceptor
=
L-sorbose
+
reduced acceptor

Synonyms

D-sorbitol dehydrogenase, FAD-SLDH, GoSLDH, SDH, SLDH, sldhAB, sorbitol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.21 D-sorbitol dehydrogenase (acceptor)

Substrates Products

Substrates Products on EC 1.1.99.21 - D-sorbitol dehydrogenase (acceptor)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-(2-hydroxyethyl)amino-1-deoxy-D-sorbitol + acceptor
6-(2-hydroxyethyl)amino-6-deoxy-L-sorbose + reduced acceptor
show the reaction diagram
1-benzyloxycarbonylamino-1-deoxy-D-sorbitol + acceptor
N-benzyloxycarbonyl-6-amino-L-sorbose + reduced acceptor
show the reaction diagram
-
-
-
-
-
D-arabitol + acceptor
D-xylulose + reduced acceptor
show the reaction diagram
-
-
-
-
?
D-glucitol + NAD+
D-fructose + NADH + H+
show the reaction diagram
D-gluconate + acceptor
5-keto-D-gluconate + reduced acceptor
show the reaction diagram
-
-
-
-
?
D-mannitol + acceptor
? + reduced acceptor
show the reaction diagram
-
oxidation at 5% the rate of D-sorbitol
-
-
?
D-mannitol + acceptor
D-fructose + reduced acceptor
show the reaction diagram
-
-
-
-
?
D-sorbitol + acceptor
L-sorbose + reduced acceptor
show the reaction diagram
D-sorbitol + acceptor
sorbose + reduced acceptor
show the reaction diagram
D-sorbitol + NADP+
L-sorbose + NADPH
show the reaction diagram
D-sorbitol + phenazine methosulfate
?
show the reaction diagram
-
the catalytic reaction follows an ordered Bi Bi mechanism, the native mSLDH bears two different substrate-binding sites, one for ubiquinone using as electron acceptor and the other for D-sorbitol, in addition to PQQ-binding and Mg2+-binding sites in the catalytic center
-
-
?
D-sorbitol + ubiquinone-2
?
show the reaction diagram
-
-
-
-
?
glycerol + acceptor
dihydroxyacetone + reduced acceptor
show the reaction diagram
-
-
-
-
?
L-glucitol + NAD+
D-sorbose + NADH + H+
show the reaction diagram
meso-erythritol + acceptor
L-erythrulose + reduced acceptor
show the reaction diagram
-
-
-
-
?
ribitol + acceptor
? + reduced acceptor
show the reaction diagram
-
-
-
-
?
additional information
?
-