1.1.98.6: ribonucleoside-triphosphate reductase (formate)

This is an abbreviated version!
For detailed information about ribonucleoside-triphosphate reductase (formate), go to the full flat file.

Word Map on EC 1.1.98.6

Reaction

ribonucleoside 5'-triphosphate
+
formate
=
2'-deoxyribonucleoside 5'-triphosphate
+
CO2
+
H2O

Synonyms

anaerobic ribonucleoside-triphosphate reductase, anaerobic ribonucleotide reductase, class III ribonucleoside-triphosphate reductase, nrdD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.98 With other, known, physiological acceptors
                1.1.98.6 ribonucleoside-triphosphate reductase (formate)

Cofactor

Cofactor on EC 1.1.98.6 - ribonucleoside-triphosphate reductase (formate)

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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
iron-sulfur centre
-
activation of enzyme involves generation of a specific amino acid free radical that is dependent on a reduced Fe-S cluster and S-adenosylmethionine
S-adenosyl-L-methionine
[4Fe-4S]-center