1.1.5.13: (S)-2-hydroxyglutarate dehydrogenase

This is an abbreviated version!
For detailed information about (S)-2-hydroxyglutarate dehydrogenase, go to the full flat file.

Reaction

Synonyms

L-2-HG dehydrogenase, L-2-hydroxyglutarate dehydrogenase, L-2-hydroxyglutarate oxygenase, L-2HG dehydrogenase, L-2HGDH, L2HG dehydrogenase, L2HG:quinone oxidoreductase, L2HGDH, lhgO, YgaF

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.5 With a quinone or similar compound as acceptor

                1.1.5.13 (S)-2-hydroxyglutarate dehydrogenase

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Results	in table
1089	AA Sequence
1	Application
4	Cloned(Commentary)
8	Cofactor
3	General Information
3	Inhibitors
5	KM Value [mM]
4	Localization
1	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
7	Organism
4	Pathway
1	pH Optimum
1	pH Range
6	Protein Variants
5	Purification (Commentary)
1	Reaction
2	Reaction Type
7	Reference
13	Source Tissue
1	Specific Activity [micromol/min/mg]
14	Substrates and Products (Substrate)
3	Subunits
22	Synonyms
1	Systematic Name
3	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.1.5.13 - (S)-2-hydroxyglutarate dehydrogenase

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SYSTEMATIC NAME

IUBMB Comments

(S)-2-hydroxyglutarate:quinone oxidoreductase

The enzyme, characterized from the bacterium Escherichia coli, contains an FAD cofactor that is not covalently attached. It is bound to the cytoplasmic membrane and is coupled to the membrane quinone pool.