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1.1.5.13: (S)-2-hydroxyglutarate dehydrogenase

This is an abbreviated version!
For detailed information about (S)-2-hydroxyglutarate dehydrogenase, go to the full flat file.

Reaction

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(S)-2-hydroxyglutarate
+
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a quinone
=
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2-oxoglutarate
+
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a quinol

Synonyms

L-2-HG dehydrogenase, L-2-hydroxyglutarate dehydrogenase, L-2-hydroxyglutarate oxygenase, L-2HG dehydrogenase, L-2HGDH, L2HG dehydrogenase, L2HG:quinone oxidoreductase, L2HGDH, lhgO, YgaF

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.5 With a quinone or similar compound as acceptor
                EC 1.1.5.131.1.5.13 (S)-2-hydroxyglutarate dehydrogenase

Systematic Name

Systematic Name on EC 1.1.5.13 - (S)-2-hydroxyglutarate dehydrogenase

for references in articles please use BRENDA:EC1.1.5.13

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SYSTEMATIC NAME
IUBMB Comments
(S)-2-hydroxyglutarate:quinone oxidoreductase
The enzyme, characterized from the bacterium Escherichia coli, contains an FAD cofactor that is not covalently attached. It is bound to the cytoplasmic membrane and is coupled to the membrane quinone pool.