1.1.3.45: aclacinomycin-N oxidase

This is an abbreviated version!
For detailed information about aclacinomycin-N oxidase, go to the full flat file.

Word Map on EC 1.1.3.45

1.1.3.45

sirtuins

deacetylation

nad+-dependent

nicotinamide

hyperacetylation

mnsod

caloric

sirt3-dependent

longevity

sirt3-mediated

sirts

sirt1-7

foxo3a

acetylome

honokiol

Reaction

Synonyms

aclacinomycin oxidoreductase, AknOx, dnrW

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.3 With oxygen as acceptor

1.1.3.45 aclacinomycin-N oxidase

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Results	in table
36	AA Sequence
1	Cloned(Commentary)
2	Cofactor
2	Crystallization (Commentary)
3	General Information
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
4	Organism
5	Pathway
11	Protein Variants
2	Purification (Commentary)
1	Reaction
4	Reference
2	Substrates and Products (Substrate)
2	Subunits
6	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 1.1.3.45 - aclacinomycin-N oxidase

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aclacinomycin-N:oxygen oxidoreductase

A flavoprotein (FAD). This bifunctional enzyme is a secreted flavin-dependent enzyme that is involved in the modification of the terminal sugar residues in the biosynthesis of aclacinomycins. The enzyme utilizes the same active site to catalyse the oxidation of the rhodinose moiety of aclacinomycin N to the cinerulose A moiety of aclacinomycin A and the oxidation of the latter to the L-aculose moiety of aclacinomycin Y (cf. EC 1.3.3.14, aclacinomycin A oxidase).