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1.1.3.18: secondary-alcohol oxidase

This is an abbreviated version!
For detailed information about secondary-alcohol oxidase, go to the full flat file.

Reaction

a secondary alcohol
+
O2
=
a ketone
+
H2O2

Synonyms

AOX1, polyvinyl alcohol oxidase, PVA oxidase, SAO, secondary alcohol oxidase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.18 secondary-alcohol oxidase

Engineering

Engineering on EC 1.1.3.18 - secondary-alcohol oxidase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
F101S
variant is less capable of converting the (S)-alcohols and does not convert any of the (R)-alcohols
L317F
mutant displays low or no significant activity with secondary alcohols and/or lower enantioselectivity than wild-type
T315S
mutant displays low or no significant activity with secondary alcohols and/or lower enantioselectivity than wild-type
W560F
mutant displays low or no significant activity with secondary alcohols and/or lower enantioselectivity than wild-type