1.1.1.B38: hydroxymethylglutaryl-CoA reductase [NAD(P)H]

This is an abbreviated version!
For detailed information about hydroxymethylglutaryl-CoA reductase [NAD(P)H], go to the full flat file.

Reaction

Synonyms

3-hydroxy-3-methylglutaryl coenzyme A reductase, AF1736, class II HMG-CoA reductase, HGMR, HMG-CoA reductase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.B38 hydroxymethylglutaryl-CoA reductase [NAD(P)H]

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	AA Sequence
2	Cloned(Commentary)
6	Cofactor
1	Crystallization (Commentary)
1	General Information
1	IC50 Value
1	Inhibitors
6	kcat/KM [mM/s]
7	KM Value [mM]
2	Natural Substrates/ Products (Substrates)
2	Organism
2	Pathway
4	pH Optimum
2	Purification (Commentary)
1	Reaction
2	Reference
4	Substrates and Products (Substrate)
1	Subunits
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
6	Turnover Number [1/s]

Natural Substrates Products

print visible entries

print all entries

Natural Substrates Products on EC 1.1.1.B38 - hydroxymethylglutaryl-CoA reductase [NAD(P)H]

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Natural Substrate Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+

mevalonate + CoA + 2 NAD+

Streptococcus pneumoniae

-

-

760596

-

-

?

3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+

mevalonate + CoA + 2 NADP+

Streptococcus pneumoniae

-

-

760596

-

-

?